Molecular modeling approaches to address drug-metabolizing enzymes (DMEs) mediated chemoresistance: a review
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DOI: 10.1080/03602532.2021.1874406
Abstract: Abstract Resistance against clinically approved anticancer drugs is the main roadblock in cancer treatment. Drug metabolizing enzymes (DMEs) that are capable of metabolizing a variety of xenobiotic get overexpressed in malignant cells, therefore, catalyzing drug… read more here.
Keywords: drug metabolizing; molecular modeling; chemoresistance; drug ... See more keywords