Metformin limits osteoarthritis development and progression through activation of AMPK signalling
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DOI: 10.1136/annrheumdis-2019-216713
Abstract: Objectives In this study, we aim to determine the effect of metformin on osteoarthritis (OA) development and progression. Methods Destabilisation of the medial meniscus (DMM) surgery was performed in 10-week-old wild type and AMP-activated protein… read more here.
Keywords: dmm surgery; development progression; metformin;