Updated results of activity of durvalumab in advanced endometrial cancer (AEC) according to mismatch repair (MMR) status: The phase II PHAEDRA trial (ANZGOG1601)
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DOI: 10.1093/annonc/mdz446.011
Abstract: Abstract Background Durvalumab monotherapy has demonstrated promising objective tumour response (OTR) and safety in advanced endometrial cancer with deficient MMR. We report here updated OTR, progression-free survival (PFS) and overall survival (OS) results based on… read more here.
Keywords: trial; pathology; honoraria self; dmmr pmmr ... See more keywords
Different surgical outcome and follow-up status between dMMR and pMMR colorectal cancer patients who fulfilled with Amsterdam-II criteria
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DOI: 10.1186/s12957-020-01976-8
Abstract: Background Although hereditary non-polyposis colorectal cancer (HNPCC) could be subtyped into proficient or deficient mismatch repair gene expression (pMMR or dMMR), distinct clinical features between these two subgroups patients were rarely reported. Methods We retrospectively… read more here.
Keywords: dmmr; colorectal cancer; dmmr pmmr; patients fulfilled ... See more keywords