Articles with "dmna" as a keyword



Intradermal Vaccination with PLGA Nanoparticles via Dissolving Microneedles and Classical Injection Needles

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Published in 2024 at "Pharmaceutical Research"

DOI: 10.1007/s11095-024-03665-7

Abstract: A dissolving microneedle array (dMNA) is a vaccine delivery device with several advantages over conventional needles. By incorporating particulate adjuvants in the form of poly(D,L-lactic-co-glycolic acid) (PLGA) nanoparticles (NPs) into the dMNA, the immune response… read more here.

Keywords: dmna; plga; cpg; plga nanoparticles ... See more keywords

ENHANCED BIOAVAILABILITY OF LOBEGLITAZONE VIA DISSOLVING MICRONEEDLE PATCHES IN RATS

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Published in 2025 at "International Journal of Applied Pharmaceutics"

DOI: 10.22159/ijap.2025v17i5.54818

Abstract: Objective: To compare the pharmacokinetics of lobeglitazone administered via oral suspension and transdermal dissolving microneedle array (DMNA) patch in rats using a validated LC-MS/MS method. Methods: Male Wistar rats were administered a single 0.5 mg/kg dose… read more here.

Keywords: oral administration; lobeglitazone; dmna; enhanced bioavailability ... See more keywords