The effect of depot medroxyprogesterone acetate on tenofovir alafenamide in rhesus macaques
Sign Up to like & getrecommendations! Published in 2020 at "Antiviral research"
DOI: 10.1016/j.antiviral.2020.105001
Abstract: Prevention of HIV infection and unintended pregnancies are public health priorities. In sub-Saharan Africa, where HIV prevalence is highest, depot medroxyprogesterone acetate (DMPA) is widely used as contraception. Therefore, understanding potential interactions between DMPA and… read more here.
Keywords: tissue; depot medroxyprogesterone; tfv; dmpa ... See more keywords
Behaviour of protein (BSA)-lipid (DMPA) mixed monolayer on the spreading order of the individual component.
Sign Up to like & getrecommendations! Published in 2019 at "Chemistry and physics of lipids"
DOI: 10.1016/j.chemphyslip.2019.104810
Abstract: Surface pressure (π) - mean molecular area (A) isotherms of protein (BSA) - lipid (DMPA) mixed films are examined by varying their ratio and altering the spreading order of BSA and DMPA on the water… read more here.
Keywords: bsa; dmpa; spreading order; protein bsa ... See more keywords
Task-shifting the provision of DMPA-SC in the DR Congo: Perspectives from two different groups of providers☆☆☆
Sign Up to like & getrecommendations! Published in 2018 at "Contraception"
DOI: 10.1016/j.contraception.2018.07.002
Abstract: Objectives To document the experience of three groups of Family Planning service providers participating in task-shifting for the provision of subcutaneous depot-medroxyprogesterone acetate (DMPA-SC) at the community level in the DRC. Study design This article… read more here.
Keywords: provision dmpa; task shifting; community; shifting provision ... See more keywords
Continuation of self-injected versus provider-administered contraception in Senegal: a nonrandomized, prospective cohort study☆☆☆★
Sign Up to like & getrecommendations! Published in 2019 at "Contraception"
DOI: 10.1016/j.contraception.2018.11.001
Abstract: Objectives The primary objective of this study was to compare the 12-month continuation rate for women who self-injected subcutaneous depot-medroxyprogesterone acetate (DMPA-SC) with that for women receiving intramuscular depot-medroxyprogesterone acetate (DMPA-IM) from a provider. This… read more here.
Keywords: provider; continuation; study; contraception ... See more keywords
The Association Between Immediate Postpartum Depot Medroxyprogesterone Acetate Use and Postpartum Depressive Symptoms.
Sign Up to like & getrecommendations! Published in 2021 at "American journal of perinatology"
DOI: 10.1055/s-0041-1739431
Abstract: OBJECTIVE While postpartum depot medroxyprogesterone acetate (DMPA) is a highly effective form of contraception, some data suggest an association with depressive symptoms. Our objective was to evaluate the relationship between receipt of DMPA in the… read more here.
Keywords: immediate postpartum; depressive symptoms; postpartum depression; postpartum ... See more keywords
Genital epithelial barrier function is conserved by intravaginal rings releasing etonogestrel and ethinyl estradiol.
Sign Up to like & getrecommendations! Published in 2023 at "Tissue barriers"
DOI: 10.1080/21688370.2023.2186672
Abstract: The injectable progestin depot-medroxyprogesterone acetate (DMPA) is a popular contraceptive choice in sub-Saharan Africa although mouse models indicate it weakens genital epithelial integrity and barrier function and increases susceptibility to genital infection. The intravaginal ring… read more here.
Keywords: barrier function; function; genital epithelial; ethinyl estradiol ... See more keywords
Is the Injectable Contraceptive Depo-Medroxyprogesterone Acetate (DMPA-IM) Associated with an Increased Risk for HIV Acquisition? The Jury Is Still Out
Sign Up to like & getrecommendations! Published in 2019 at "AIDS Research and Human Retroviruses"
DOI: 10.1089/aid.2019.0228
Abstract: Intramuscular depo-medroxyprogesterone acetate (DMPA-IM) is the most widely used hormonal contraceptive in sub-Saharan Africa. Previous meta-analyses of observational studies found a significant 40%–50% increased risk associated with DMPA-IM use, relative to no contraception or infrequent… read more here.
Keywords: risk; use; hiv risk; hiv ... See more keywords
Self-injected contraceptives: does the investment reflect women’s preferences?
Sign Up to like & getrecommendations! Published in 2022 at "BMJ Global Health"
DOI: 10.1136/bmjgh-2022-008862
Abstract: Subcutaneous depot medroxyprogesterone acetate (DMPA-SC) is an innovative contraceptive method aimed at meeting women’s unique circumstances and needs, largely due to its ability to be self-injected. Substantial research and advocacy investments have been made to… read more here.
Keywords: self injected; self injection; research; dmpa ... See more keywords
Benefits, anxieties, acceptance, and barriers to the new injectable contraceptive DMPA-SC (Sayana Press): Clients’ perceptions in Sindh, Pakistan
Sign Up to like & getrecommendations! Published in 2023 at "Gates Open Research"
DOI: 10.12688/gatesopenres.14326.1
Abstract: Background: Injections are Pakistan's third most preferred contraceptive method because of their convenience. They represent a 2.5% share of the contraceptive prevalence rate (CPR) and contribute 10% to the current CPR. However, injections require a… read more here.
Keywords: injection; dmpa sayana; sayana press; dmpa ... See more keywords
Multi-omics analysis of the cervical epithelial integrity of women using depot medroxyprogesterone acetate
Sign Up to like & getrecommendations! Published in 2022 at "PLoS Pathogens"
DOI: 10.1371/journal.ppat.1010494
Abstract: Depot medroxyprogesterone acetate (DMPA) is an injectable hormonal contraceptive used by millions of women worldwide. However, experimental studies have associated DMPA use with genital epithelial barrier disruption and mucosal influx of human immunodeficiency virus (HIV)… read more here.
Keywords: depot medroxyprogesterone; analysis; medroxyprogesterone acetate; dmpa ... See more keywords
Differential Elevation of Inflammation and CD4+ T Cell Activation in Kenyan Female Sex Workers and Non-Sex Workers Using Depot-Medroxyprogesterone Acetate
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2020.598307
Abstract: Background Depot Medroxyprogesterone (DMPA) is one of the most widely used contraceptives in Sub-Saharan Africa where HIV incidence is high. We explored the effect of DMPA on the activation of HIV cellular targets and inflammation… read more here.
Keywords: sex; activation; dmpa; cd4 ... See more keywords