Comment on “Epigenetics in the pathogenesis of RA”
Sign Up to like & getrecommendations! Published in 2017 at "Seminars in Immunopathology"
DOI: 10.1007/s00281-017-0638-9
Abstract: Dear Editors, Rheumatoid arthritis (RA) is a chronic autoimmune disorder that affects between 0.5 and 1% of individuals in the more economically developed countries [1]. The cause of the disease is yet to be determined,… read more here.
Keywords: dmrs; immunopathology; study; twin pairs ... See more keywords
Developmental origins of transgenerational sperm DNA methylation epimutations following ancestral DDT exposure.
Sign Up to like & getrecommendations! Published in 2019 at "Developmental biology"
DOI: 10.1016/j.ydbio.2018.11.016
Abstract: Epigenetic alterations in the germline can be triggered by a number of different environmental factors from diet to toxicants. These environmentally induced germline changes can promote the epigenetic transgenerational inheritance of disease and phenotypic variation.… read more here.
Keywords: dmrs; developmental origins; inheritance; sperm ... See more keywords
Preconception urinary phthalate concentrations and sperm DNA methylation profiles among men undergoing IVF treatment: a cross-sectional study
Sign Up to like & getrecommendations! Published in 2017 at "Human Reproduction"
DOI: 10.1093/humrep/dex283
Abstract: STUDY QUESTION Are preconception phthalate and phthalate replacements associated with sperm differentially methylated regions (DMRs) among men undergoing IVF? SUMMARY ANSWER Ten phthalate metabolites were associated with 131 sperm DMRs that were enriched in genes… read more here.
Keywords: preconception; phthalate; dmrs; sperm dna ... See more keywords
Cell type‐specific DNA methylation analysis of the prefrontal cortex of patients with schizophrenia
Sign Up to like & getrecommendations! Published in 2021 at "Psychiatry and Clinical Neurosciences"
DOI: 10.1111/pcn.13282
Abstract: Epigenetics reflects complex interactions between genes and the environment and plays a role in long-lasting gene expression changes. Therefore, unraveling epigenetic landscape of brain cells from patients with psychiatric disorders will contribute to understanding the… read more here.
Keywords: schizophrenia; dmrs; analysis; gene ... See more keywords
Epigenomic Signatures in Myelodysplastic Syndrome Patients As Predictors of Donor Compatibility and Transplant Outcome
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DOI: 10.1182/blood-2019-127124
Abstract: Myelodysplastic syndromes (MDS) are a heterogeneous group of hematopoietic stem cell disorders for which allogeneic hematopoietic stem cell transplantation (HCT) is currently the only curative treatment. Epigenetic lesions are considered a major pathogenetic determinant in… read more here.
Keywords: methylation; relapsed patients; dmrs; transplant ... See more keywords
Long-Lasting Defence Priming by β-Aminobutyric Acid in Tomato Is Marked by Genome-Wide Changes in DNA Methylation
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Plant Science"
DOI: 10.3389/fpls.2022.836326
Abstract: Exposure of plants to stress conditions or to certain chemical elicitors can establish a primed state, whereby responses to future stress encounters are enhanced. Stress priming can be long-lasting and likely involves epigenetic regulation of… read more here.
Keywords: methylation; dmrs; aminobutyric acid; genome wide ... See more keywords
Genome-Wide Methylation Patterns in Androgen-Independent Prostate Cancer Cells: A Comprehensive Analysis Combining MeDIP-Bisulfite, RNA, and microRNA Sequencing Data
Sign Up to like & getrecommendations! Published in 2018 at "Genes"
DOI: 10.3390/genes9010032
Abstract: This study aimed to investigate the mechanisms underlying the development of the androgen-independent phenotype in prostate cancer. Methylation patterns were detected in androgen-independent and androgen-dependent lymph node carcinoma of the prostate (LNCaP) prostate carcinoma cells… read more here.
Keywords: prostate; methylation; dmrs; androgen independent ... See more keywords