Study Finds Key Mechanism within Genomic Region Important for Sex Determination in Vertebrates.
Sign Up to like & getrecommendations! Published in 2017 at "Molecular biology and evolution"
DOI: 10.1093/molbev/msw287
Abstract: In various vertebrate species, including fish, amphibians, reptiles, birds and mammals, the DMRT1 gene is a master sex regulator, working to develop and maintain “maleness”— either the sex cells (or germline) into testis and/or maintaining… read more here.
Keywords: sex; key mechanism; dmrt1; gene ... See more keywords
Transcription factor Dmrt1 triggers the SPRY1-NF-κB pathway to maintain testicular immune homeostasis and male fertility
Sign Up to like & getrecommendations! Published in 2023 at "Zoological Research"
DOI: 10.24272/j.issn.2095-8137.2022.440
Abstract: Bacterial or viral infections, such as Brucella, mumps virus, herpes simplex virus, and Zika virus, destroy immune homeostasis of the testes, leading to spermatogenesis disorder and infertility. Of note, recent research shows that SARS-CoV-2 can… read more here.
Keywords: male; testicular immune; immune homeostasis; factor ... See more keywords