Dmrt2 promotes transition of endochondral bone formation by linking Sox9 and Runx2
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DOI: 10.1038/s42003-021-01848-1
Abstract: Endochondral bone formation is fundamental for skeletal development. During this process, chondrocytes undergo multiple steps of differentiation and coordinated transition from a proliferating to a hypertrophic stage, which is critical to advance skeletal development. Here,… read more here.
Keywords: bone formation; runx2; dmrt2; endochondral bone ... See more keywords
DMRT2 Interacts With FXR and Improves Insulin Resistance in Adipocytes and a Mouse Model
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2021.723623
Abstract: Insulin resistance (IR) plays a critical role in cardiovascular diseases and metabolic diseases. In this study, we identified the downregulation of DMRT2 in adipose tissues from insulin-resistant subjects through bioinformatics analysis and in an insulin-resistant… read more here.
Keywords: insulin resistant; resistance; insulin resistance; model ... See more keywords