Pharmacological studies on the NOP and opioid receptor agonist PWT2‐[Dmt1]N/OFQ(1‐13)
Sign Up to like & getrecommendations! Published in 2017 at "European Journal of Pharmacology"
DOI: 10.1016/j.ejphar.2016.11.026
Abstract: &NA; An innovative chemical strategy named peptide welding technology (PWT) has been developed for the facile synthesis of tetrabranched peptides. [Dmt1]N/OFQ(1–13)‐NH2 acts as a universal agonist for nociceptin/orphanin FQ (N/OFQ) and classical opioid receptors. The… read more here.
Keywords: dmt1; ofq nh2; dmt1 ofq; pwt2 dmt1 ... See more keywords
DMT1 and iron transport
Sign Up to like & getrecommendations! Published in 2019 at "Free Radical Biology and Medicine"
DOI: 10.1016/j.freeradbiomed.2018.07.020
Abstract: ABSTRACT Many past and recent advances in the field of iron metabolism have relied upon the discovery of divalent metal transporter 1, DMT1 in 1997. DMT1 is the major iron transporter and contributes non‐heme iron… read more here.
Keywords: dmt1 iron; dmt1; transport; dmt1 expression ... See more keywords
DMT1 Expression and Iron Levels at the Crossroads Between Aging and Neurodegeneration
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DOI: 10.3389/fnins.2019.00575
Abstract: Iron homeostasis is an essential prerequisite for metabolic and neurological functions throughout the healthy human life, with a dynamic interplay between intracellular and systemic iron metabolism. The development of different neurodegenerative diseases is associated with… read more here.
Keywords: aging neurodegeneration; dmt1; dmt1 expression; expression iron ... See more keywords
Effect of Bis(maltolato)oxovanadium(IV) on Zinc, Copper, and Manganese Homeostasis and DMT1 mRNA Expression in Streptozotocin-Induced Hyperglycemic Rats
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DOI: 10.3390/biology11060814
Abstract: Simple Summary Diabetes mellitus is a disease that affects some metabolic processes, altering the metabolism of trace elements associated with the antioxidant defense system. The insulin-mimetic activity of vanadium has received attention in recent years.… read more here.
Keywords: expression; copper manganese; homeostasis; zinc copper ... See more keywords