Comparative Effectiveness of Rituximab and Other Initial Treatment Choices for Multiple Sclerosis
Sign Up to like & getrecommendations! Published in 2018 at "JAMA Neurology"
DOI: 10.1001/jamaneurol.2017.4011
Abstract: Importance Comparative real-world effectiveness studies of initial disease-modifying treatment (DMT) choices for relapsing-remitting multiple sclerosis (RRMS) that include rituximab are lacking. Objective To assess the effectiveness and drug discontinuation rates of rituximab among patients with… read more here.
Keywords: dmts; initial treatment; treatment; discontinuation ... See more keywords
Intramuscular dimethyl trisulfide: efficacy in a large swine model of acute severe cyanide toxicity
Sign Up to like & getrecommendations! Published in 2019 at "Clinical Toxicology"
DOI: 10.1080/15563650.2018.1511800
Abstract: Abstract Background: Cyanide is a deadly compound used as a terrorist agent. Current FDA approved antidotes require intravenous administration, limiting their utility in a mass casualty scenario. Dimethyl trisulfide (DMTS), a sulfur-based molecule, binds cyanide… read more here.
Keywords: dmts; cyanide toxicity; swine model; model acute ... See more keywords
Self‐injectable DMTs in relapsing MS: NEDA assessment at 10 years in a real‐world cohort
Sign Up to like & getrecommendations! Published in 2022 at "Acta Neurologica Scandinavica"
DOI: 10.1111/ane.13582
Abstract: Multiple sclerosis (MS) is an immune‐mediated disorder of the central nervous system. DMTs effectively reduce the annual relapse rate—thus reducing disease activity—and, to a lesser extent, some DMTs prevent disease progression in some people with… read more here.
Keywords: neda assessment; relapsing neda; dmts; injectable dmts ... See more keywords
Vaccine Response in Patients With Multiple Sclerosis Receiving Teriflunomide
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Neurology"
DOI: 10.3389/fneur.2022.828616
Abstract: Many patients with multiple sclerosis (MS) receive disease-modifying therapies (DMTs), such as teriflunomide, to reduce disease activity and slow progression. DMTs mediate their efficacy by modulating or suppressing the immune system, which might affect a… read more here.
Keywords: response; vaccination; dmts; vaccine response ... See more keywords