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Published in 2022 at "Research in veterinary science"
DOI: 10.1016/j.rvsc.2022.03.006
Abstract: Degenerative mitral valve disease (DMVD) is a common cause of pulmonary hypertension (PH) in dogs. Medial thickening of the pulmonary artery is a common histopathological change in PH. The cause of medial thickening could be…
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Keywords:
mitral valve;
group;
dmvd group;
pulmonary artery ... See more keywords
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Published in 2019 at "Journal of Veterinary Internal Medicine"
DOI: 10.1111/jvim.15347
Abstract: Background Pathophysiologic mechanisms for the development and progression of degenerative mitral valve disease (DMVD) remain elusive. Increased concentrations of circulating trimethylamine N‐oxide (TMAO) and its precursors choline and l‐carnitine are associated with the presence and…
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Keywords:
dmvd;
heart;
degenerative mitral;
disease ... See more keywords
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Published in 2020 at "Frontiers in Veterinary Science"
DOI: 10.3389/fvets.2020.612130
Abstract: Background: Pulmonary hypertension (PH) can cause medial thickening, a hallmark of pulmonary arterial remodeling. The serotonin (5HT) pathway has been suggested as a factor associated with PH by inducing pulmonary arterial smooth muscle cells (SMCs)…
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Keywords:
dmvd;
expression proteins;
5ht pathway;
proteins related ... See more keywords