Capture-SELEX of DNA Aptamers for Estradiol Specifically and Estrogenic Compounds Collectively.
Sign Up to like & getrecommendations! Published in 2022 at "Environmental science & technology"
DOI: 10.1021/acs.est.2c05808
Abstract: Estrogenic compounds such as estrone (E1), 17β-estradiol (E2), and 17α-ethynylestradiol (EE2) are serious environmental contaminants due to their potent biological activities. At least six selections were previously reported to obtain DNA aptamers for E2, highlighting… read more here.
Keywords: aptamers estradiol; estradiol specifically; estrogenic compounds; capture selex ... See more keywords
Structure-guided development of Pb2+-binding DNA aptamers
Sign Up to like & getrecommendations! Published in 2022 at "Scientific Reports"
DOI: 10.1038/s41598-021-04243-2
Abstract: Owing to its great threat to human health and environment, Pb 2+ pollution has been recognized as a major public problem by the World Health Organization (WHO). Many DNA aptamers have been utilized in the… read more here.
Keywords: development; structure guided; dna aptamers; development pb2 ... See more keywords
In silicopost-SELEX screening and experimental characterizations for acquisition of high affinity DNA aptamers against carcinoembryonic antigen
Sign Up to like & getrecommendations! Published in 2019 at "RSC Advances"
DOI: 10.1039/c8ra10163a
Abstract: High affinity DNA aptamers against carcinoembryonic antigen were selected and verified by using anin silicoapproach and experimental characterizations. read more here.
Keywords: carcinoembryonic antigen; dna aptamers; experimental characterizations; affinity dna ... See more keywords
Immobilized DNA aptamers used as potent attractors for vascular endothelial cell: in vitro study of female rat
Sign Up to like & getrecommendations! Published in 2020 at "Bioscience Reports"
DOI: 10.1042/bsr20182444
Abstract: Abstract Vascular endothelial cells are essential to vascular function and maintenance. Dysfunction of these cells can lead to the development of cardiovascular disease or contribute to tumorigenesis. As such, the therapeutic modulation and monitoring of… read more here.
Keywords: vascular endothelial; dna aptamers; study; cell ... See more keywords
Evolution of a highly functional circular DNA aptamer in serum
Sign Up to like & getrecommendations! Published in 2020 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkaa800
Abstract: Abstract Circular DNA aptamers are powerful candidates for therapeutic applications given their dramatically enhanced biostability. Herein we report the first effort to evolve circular DNA aptamers that bind a human protein directly in serum, a… read more here.
Keywords: circular dna; dna; serum; dna aptamers ... See more keywords
Molecular affinity rulers: systematic evaluation of DNA aptamers for their applicabilities in ELISA
Sign Up to like & getrecommendations! Published in 2019 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkz688
Abstract: Abstract Many nucleic acid aptamers that bind to target molecules have been reported as antibody alternatives. However, while the affinities of aptamers vary widely, little is known about the relationship between the affinities and their… read more here.
Keywords: affinity rulers; molecular affinity; affinity; aptamers applicabilities ... See more keywords
Single-stranded DNA aptamer-based rolling circle amplification as anti-chicken Salmonella bacteriostatic
Sign Up to like & getrecommendations! Published in 2022 at "Veterinary World"
DOI: 10.14202/vetworld.2022.1171-1176
Abstract: Background and Aim: Salmonella is a major foodborne pathogen in the poultry industry, wherein the control measures may include sanitation and antibacterial and vaccines. However, there have been severe global restrictions on using anti-Salmonella antibacterial… read more here.
Keywords: dna aptamer; single stranded; dna; salmonella ... See more keywords
Simple and cheap CRISPR/Cas12a biosensor based on plug-and-play of DNA aptamers for the detection of endocrine-disrupting compounds.
Sign Up to like & getrecommendations! Published in 2023 at "Talanta"
DOI: 10.2139/ssrn.4397245
Abstract: Endocrine-disrupting compounds (EDCs) are widely distributed in the environment. Here, we present a CRISPR/Cas12a (CAS) biosensor based on DNA aptamers for point-of-care detection of EDCs. Two typical EDCs, 17β-estradiol (E2) and bisphenol A (BPA), were… read more here.
Keywords: dna; biosensor based; disrupting compounds; dna aptamers ... See more keywords
DNA Aptamers Block the Receptor Binding Domain at the Spike Protein of SARS-CoV-2
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2021.713003
Abstract: DNA aptamers are versatile molecular species obtained by the folding of short single-stranded nucleotide sequences, with highly specific recognition capabilities against proteins. Here we test the ability of DNA aptamers to interact with the spike… read more here.
Keywords: protein sars; dna aptamers; spike protein; sars cov ... See more keywords
Putative Mechanisms Underlying High Inhibitory Activities of Bimodular DNA Aptamers to Thrombin
Sign Up to like & getrecommendations! Published in 2019 at "Biomolecules"
DOI: 10.3390/biom9020041
Abstract: Nucleic acid aptamers are prospective molecular recognizing elements. Similar to antibodies, aptamers are capable of providing specific recognition due to their spatial structure. However, the apparent simplicity of oligonucleotide folding is often elusive, as there… read more here.
Keywords: dna aptamers; putative mechanisms; mechanisms underlying; high inhibitory ... See more keywords
Analysis of the Interaction between DNA Aptamers and Cytochrome C on the Surface of Lipid Films and on the MUA Monolayer: A QCM-D Study
Sign Up to like & getrecommendations! Published in 2023 at "Biosensors"
DOI: 10.3390/bios13020251
Abstract: We analyzed the possibility of the detection of cytochrome c (cyt c) being physically adsorbed on lipid films or covalently bounded to 11-mercapto-1-undecanoic acid (MUA) chemisorbed on the gold layer using quartz crystal microbalance with… read more here.
Keywords: interaction; dna; surface; lipid films ... See more keywords