Gold(III) complex from pyrimidine and morpholine analogue Schiff base ligand: Synthesis, characterization, DFT, TDDFT, catalytic, anticancer, molecular modeling with DNA and BSA and DNA binding studies
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Molecular Liquids"
DOI: 10.1016/j.molliq.2019.111655
Abstract: Abstract New gold(III) complex, [AuL2]Cl3 was synthesized from (2-(4-morpholinobenzylidene)-1-(4-(trifluoromethyl)pyrimidin-2-yl)hydrazine) and characterized by analytical and miscellaneous spectral methods. These results show that Au(III) complex has square planar geometry. Density functional theory (DFT) calculations have been done… read more here.
Keywords: dna bsa; ligand; ligand complex; iii complex ... See more keywords
Unravelling the self-assembly of a novel cationic pseudo-gemini surfactant and its monomeric counterpart: interactions with DNA and BSA in aqueous medium at neutral pH.
Sign Up to like & getrecommendations! Published in 2025 at "Soft matter"
DOI: 10.1039/d5sm00075k
Abstract: The demand for sustainable, efficient, and easily tunable cationic surfactants is growing rapidly due to their pivotal role in gene therapy, drug delivery, and biotechnology. However, conventional gemini surfactants often require laborious synthesis and lack… read more here.
Keywords: gemini; unravelling self; dna bsa; gemini surfactant ... See more keywords
Investigation of DNA/BSA binding of three Ru(II) complexes by various spectroscopic methods, molecular docking and their antimicrobial activity
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Coordination Chemistry"
DOI: 10.1080/00958972.2017.1407410
Abstract: Abstract An intercalative ligand, ppip (ppip = {2-(4-(piperidin-1-yl)phenyl)-1H-imidazo[4,5-f][1,10]phenanthroline}), and its mononuclear Ru(II) polypyridyl complexes, [Ru(phen)2(ppip)]2+ (1) (phen=1,10-phenanthrolene), [Ru(bpy)2(ppip)]2+ (2) (bpy=2,2′-bipyridine) and [Ru(dmb)2(ppip)]2+ (3) (dmb=4,4′-dimethyl-2,2′-bipyridine), have been synthesized and characterized by elemental analysis and spectroscopic techniques… read more here.
Keywords: ppip; antimicrobial activity; bsa binding; molecular docking ... See more keywords
Synthesis of oxidovanadium complexes containing coumarin and naphthalene: bromoperoxidase activity and DNA/BSA binding
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Coordination Chemistry"
DOI: 10.1080/00958972.2023.2205002
Abstract: Abstract Two tridentate Schiff base ligands, L1 and L2 , have been introduced in the synthesis of mononuclear oxidovanadium complexes with a co-ligand 1,10-phenanthroline. Two mononuclear complexes, [VO(L1)(1,10-phen)] (1) and [VO(L2)(1,10-phen)] (2), have been synthesized… read more here.
Keywords: oxidovanadium complexes; dna bsa; synthesis;
Anticancer activities and DNA/BSA interactions for five Cu(II) compounds with substituted terpyridine ligands
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Coordination Chemistry"
DOI: 10.1080/00958972.2023.2209270
Abstract: Abstract The reactions of copper chloride and 4′-(4′-substituted-phenyl)-2,2′:6′,2′′-terpyridine ligands bearing nitro (L1 ), methyl (L2 ), phenyl (L3 ), tolyl (L4 ) and carboxyl (L5 ) gave five copper compounds (1–5) which have mononuclear structures… read more here.
Keywords: spectroscopy; anticancer activities; activities dna; dna bsa ... See more keywords
Anticancer and Cytotoxic Activities of [Cu(C6H16N2O2)2][Ni(CN)4] and [Cu(C6H16N2O2)Pd(CN)4] Cyanidometallate Compounds on HT29, HeLa, C6 and Vero Cell Lines.
Sign Up to like & getrecommendations! Published in 2017 at "Anti-cancer agents in medicinal chemistry"
DOI: 10.2174/1871520617666170103102417
Abstract: BACKGROUND In cancer, apoptosis relevant proteins-such as CaM kinase, Bcl-2 or P53, topoisomerase I, cell migration feature and DNA/BSA-macromolecules represent significant targets for current chemotherapeutics. OBJECTIVE We recently reported two coordination compounds-[Cu(C6H16N2O2)2][Ni(CN)4] (1) and [Cu(C6H16… read more here.
Keywords: anticancer cytotoxic; cytotoxic activities; vero; spectroscopy ... See more keywords
An Integrated Analysis of Mechanistic Insights into Biomolecular Interactions and Molecular Dynamics of Bio-Inspired Cu(II) and Zn(II) Complexes towards DNA/BSA/SARS-CoV-2 3CLpro by Molecular Docking-Based Virtual Screening and FRET Detection
Sign Up to like & getrecommendations! Published in 2022 at "Biomolecules"
DOI: 10.3390/biom12121883
Abstract: Novel constructed bioactive mixed-ligand complexes (1b) [CuII(L)2(phen)] and (2b) [ZnII(L)2(phen)] {where, L = 2-(4-morpholinobenzylideneamino)phenol), phen = 1,10-phenanthroline} have been structurally analysed by various analytical and spectroscopic techniques, including, magnetic moments, thermogravimetric analysis, and X-ray crystallography.… read more here.
Keywords: molecular docking; cov 3clpro; fret detection; dna bsa ... See more keywords
DNA and BSA Binding, Molecular Docking Interactions and ADMET Properties of New PEPPSI-Type Palladium Complexes
Sign Up to like & getrecommendations! Published in 2025 at "Inorganics"
DOI: 10.3390/inorganics13120391
Abstract: Five novel PEPPSI-type palladium(II) complexes, dichloro[1-isopropyl-3-(arylmethyl)-5,6-dimethylbenzimidazolin-2-ylidene]pyridine palladium(II), were synthesized and characterized through nuclear magnetic resonance and Fourier-transform infrared spectroscopy. The DNA- and BSA-binding analyses of PEPPSI-type palladium (II) complexes were performed with UV-Vis spectroscopy by… read more here.
Keywords: spectroscopy; palladium complexes; dna bsa; type palladium ... See more keywords