Gold(III) complex from pyrimidine and morpholine analogue Schiff base ligand: Synthesis, characterization, DFT, TDDFT, catalytic, anticancer, molecular modeling with DNA and BSA and DNA binding studies
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Molecular Liquids"
DOI: 10.1016/j.molliq.2019.111655
Abstract: Abstract New gold(III) complex, [AuL2]Cl3 was synthesized from (2-(4-morpholinobenzylidene)-1-(4-(trifluoromethyl)pyrimidin-2-yl)hydrazine) and characterized by analytical and miscellaneous spectral methods. These results show that Au(III) complex has square planar geometry. Density functional theory (DFT) calculations have been done… read more here.
Keywords: dna bsa; ligand; ligand complex; iii complex ... See more keywords
Investigation of DNA/BSA binding of three Ru(II) complexes by various spectroscopic methods, molecular docking and their antimicrobial activity
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Coordination Chemistry"
DOI: 10.1080/00958972.2017.1407410
Abstract: Abstract An intercalative ligand, ppip (ppip = {2-(4-(piperidin-1-yl)phenyl)-1H-imidazo[4,5-f][1,10]phenanthroline}), and its mononuclear Ru(II) polypyridyl complexes, [Ru(phen)2(ppip)]2+ (1) (phen=1,10-phenanthrolene), [Ru(bpy)2(ppip)]2+ (2) (bpy=2,2′-bipyridine) and [Ru(dmb)2(ppip)]2+ (3) (dmb=4,4′-dimethyl-2,2′-bipyridine), have been synthesized and characterized by elemental analysis and spectroscopic techniques… read more here.
Keywords: ppip; antimicrobial activity; bsa binding; molecular docking ... See more keywords
Synthesis of oxidovanadium complexes containing coumarin and naphthalene: bromoperoxidase activity and DNA/BSA binding
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Coordination Chemistry"
DOI: 10.1080/00958972.2023.2205002
Abstract: Abstract Two tridentate Schiff base ligands, L1 and L2 , have been introduced in the synthesis of mononuclear oxidovanadium complexes with a co-ligand 1,10-phenanthroline. Two mononuclear complexes, [VO(L1)(1,10-phen)] (1) and [VO(L2)(1,10-phen)] (2), have been synthesized… read more here.
Keywords: oxidovanadium complexes; dna bsa; synthesis;
Anticancer activities and DNA/BSA interactions for five Cu(II) compounds with substituted terpyridine ligands
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Coordination Chemistry"
DOI: 10.1080/00958972.2023.2209270
Abstract: Abstract The reactions of copper chloride and 4′-(4′-substituted-phenyl)-2,2′:6′,2′′-terpyridine ligands bearing nitro (L1 ), methyl (L2 ), phenyl (L3 ), tolyl (L4 ) and carboxyl (L5 ) gave five copper compounds (1–5) which have mononuclear structures… read more here.
Keywords: spectroscopy; anticancer activities; activities dna; dna bsa ... See more keywords
Anticancer and Cytotoxic Activities of [Cu(C6H16N2O2)2][Ni(CN)4] and [Cu(C6H16N2O2)Pd(CN)4] Cyanidometallate Compounds on HT29, HeLa, C6 and Vero Cell Lines.
Sign Up to like & getrecommendations! Published in 2017 at "Anti-cancer agents in medicinal chemistry"
DOI: 10.2174/1871520617666170103102417
Abstract: BACKGROUND In cancer, apoptosis relevant proteins-such as CaM kinase, Bcl-2 or P53, topoisomerase I, cell migration feature and DNA/BSA-macromolecules represent significant targets for current chemotherapeutics. OBJECTIVE We recently reported two coordination compounds-[Cu(C6H16N2O2)2][Ni(CN)4] (1) and [Cu(C6H16… read more here.
Keywords: anticancer cytotoxic; cytotoxic activities; vero; spectroscopy ... See more keywords
An Integrated Analysis of Mechanistic Insights into Biomolecular Interactions and Molecular Dynamics of Bio-Inspired Cu(II) and Zn(II) Complexes towards DNA/BSA/SARS-CoV-2 3CLpro by Molecular Docking-Based Virtual Screening and FRET Detection
Sign Up to like & getrecommendations! Published in 2022 at "Biomolecules"
DOI: 10.3390/biom12121883
Abstract: Novel constructed bioactive mixed-ligand complexes (1b) [CuII(L)2(phen)] and (2b) [ZnII(L)2(phen)] {where, L = 2-(4-morpholinobenzylideneamino)phenol), phen = 1,10-phenanthroline} have been structurally analysed by various analytical and spectroscopic techniques, including, magnetic moments, thermogravimetric analysis, and X-ray crystallography.… read more here.
Keywords: molecular docking; cov 3clpro; fret detection; dna bsa ... See more keywords