Single-Molecule Biosensing of Alkaline Phosphatase in Cells and Serum Based on Dephosphorylation-Triggered Catalytic Assembly and Disassembly of the Fluorescent DNA Chain.
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DOI: 10.1021/acs.analchem.2c00603
Abstract: Alkaline phosphatase (ALP) is a valuable biomarker and effective therapeutic target for the diagnosis and treatment of diverse human diseases, including bone disorder, cardiovascular disease, and cancers. The reported ALP assays often suffer from laborious… read more here.
Keywords: single molecule; fluorescent dna; detection; alkaline phosphatase ... See more keywords