Intracellular positioning systems limit the entropic eviction of secondary replicons toward the nucleoid edges in bacterial cells.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of molecular biology"
DOI: 10.1016/j.jmb.2019.11.027
Abstract: Bacterial genomes, organized intracellularly as nucleoids, are composed of a main chromosome coexisting with different types of secondary replicons. Secondary replicons are major drivers of bacterial adaptation by gene exchange. They are highly diverse in… read more here.
Keywords: intracellular positioning; positioning systems; secondary replicons; systems limit ... See more keywords
Small DNA circles as bacterial topoisomerase I inhibitors
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DOI: 10.1039/c9ra02398d
Abstract: It is demonstrated that small DNA circles showed high inhibitory effect on the activity of bacterial topoisomerase I and the single-stranded regions associated with bending deformation are believed to be the crucial factor for trapping… read more here.
Keywords: circles bacterial; small dna; bacterial topoisomerase; dna circles ... See more keywords
DNA circles promote yeast ageing in part through stimulating the reorganization of nuclear pore complexes
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DOI: 10.7554/elife.71196
Abstract: The nuclear pore complex (NPC) mediates nearly all exchanges between nucleus and cytoplasm, and in many species, it changes composition as the organism ages. However, how these changes arise and whether they contribute themselves to… read more here.
Keywords: circles promote; promote yeast; nuclear pore; dna circles ... See more keywords