Mechanism of antioxidant properties of quercetin and quercetin-DNA complex
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Molecular Modeling"
DOI: 10.1007/s00894-020-04356-x
Abstract: Quercetin is the most abundant flavonoid with potent antioxidant activities. In the current research, the antioxidant properties of quercetin and quercetin-DNA complex were investigated theoretically and experimentally. Free radical scavenging experiments with thiobarbituric acid–reactive substances… read more here.
Keywords: quercetin dna; properties quercetin; dna complex; dna ... See more keywords
Investigation of binding characteristics of ritonavir with calf thymus DNA with the help of spectroscopic techniques and molecular simulation
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Biomolecular Structure and Dynamics"
DOI: 10.1080/07391102.2020.1844057
Abstract: Abstract The binding behavior of ritonavir (RTV), a HIV/AIDS protease inhibitor, with ct-DNA was characterized through multiple testing technologies and theoretical calculation. The findings revealed that the RTV–DNA complex was formed through the noncovalent interaction… read more here.
Keywords: dna; rtv; investigation binding; binding characteristics ... See more keywords
An SVM-based method for assessment of transcription factor-DNA complex models
Sign Up to like & getrecommendations! Published in 2018 at "BMC Bioinformatics"
DOI: 10.1186/s12859-018-2538-y
Abstract: BackgroundAtomic details of protein-DNA complexes can provide insightful information for better understanding of the function and binding specificity of DNA binding proteins. In addition to experimental methods for solving protein-DNA complex structures, protein-DNA docking can… read more here.
Keywords: transcription; dna complex; complex models; dna ... See more keywords
NETosis in Psoriatic Arthritis: Serum MPO–DNA Complex Level Correlates With Its Disease Activity
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.911347
Abstract: Background Neutrophil extracellular trap formation (NETosis) has been rarely reported in psoriatic arthritis (PsA). We aimed to explore the involvement of NETosis in the inflammation of PsA. Methods Serum myeloperoxidase–DNA (MPO-DNA) complex was detected by… read more here.
Keywords: dna; level; mpo dna; serum mpo ... See more keywords
Structural Rearrangement of Dps-DNA Complex Caused by Divalent Mg and Fe Cations
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms22116056
Abstract: Two independent, complementary methods of structural analysis were used to elucidate the effect of divalent magnesium and iron cations on the structure of the protective Dps-DNA complex. Small-angle X-ray scattering (SAXS) and cryo-electron microscopy (cryo-EM)… read more here.
Keywords: dna complex; dna; dps dna; cryo ... See more keywords
Markers of NETosis in Patients with Systemic Lupus Erythematosus and Antiphospholipid Syndrome
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24119210
Abstract: Neutrophil Extracellular Traps (NETs) have been implicated in systemic lupus erythematosus (SLE) and antiphospholipid syndrome (APS) pathogenesis. The myeloperoxidase–deoxyribonucleic acid (MPO-DNA) complex and nucleosomes are serum markers of NETosis. The aim of this study was… read more here.
Keywords: dna; sle aps; mpo dna; antiphospholipid syndrome ... See more keywords