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Published in 2021 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1290-3_17
Abstract: Optical tweezers enable the isolation and mechanical manipulation of individual nucleoprotein complexes. Here, we describe how to use this technique to interrogate the mechanical properties of individual protein-DNA complexes and extract information about their overall…
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Keywords:
optical tweezers;
investigate structure;
dna;
protein dna ... See more keywords
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Published in 2021 at "Polymer"
DOI: 10.1016/j.polymer.2021.124277
Abstract: Abstract DNA complexes with cetyltrimethylammonium chloride (CTMA), benzyldimethylhexadecylammonium chloride (BAC) and hexadecylpyridinium chloride (HDP) surfactants as powder samples were studied by Fourier-Transform Middle Infrared spectroscopy, X-ray diffraction and dielectric spectroscopy methods. Complexation as electrostatic interactions…
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Keywords:
characterization dna;
dna;
dna complexes;
physicochemical characterization ... See more keywords
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Published in 2017 at "Journal of chemical theory and computation"
DOI: 10.1021/acs.jctc.7b00849
Abstract: Nucleotide-sequence-dependent interactions between proteins and DNA are responsible for a wide range of gene regulatory functions. Accurate and generalizable methods to evaluate the strength of protein-DNA binding have long been sought. While numerous computational approaches…
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Keywords:
energy calculations;
dna;
protein dna;
dna complexes ... See more keywords
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Published in 2018 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.8b17013
Abstract: DNA nanotechnology has laid a platform to construct a variety of custom-shaped nanoscale objects for functionalization of specific target materials to achieve programmability and molecular recognition. Herein, we prepared DNA nanostructures [namely, synthetic DNA rings…
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Keywords:
microscopy;
dna;
dna complexes;
prostate cancer ... See more keywords
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Published in 2025 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.5c01823
Abstract: Measurement of the conformation of DNA in protein–DNA complexes is important to decipher the role of the DNA conformation and dynamics in protein recognition and function. In this work, we report a rigid nucleotide-independent spin…
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Keywords:
conformation;
protein;
dna complexes;
dna ... See more keywords
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Published in 2020 at "Journal of the American Society for Mass Spectrometry"
DOI: 10.1021/jasms.9b00145
Abstract: Inorganic salts and nonvolatile-buffer components affect the structure and stability of proteins, and some protein complexes are unable to maintain their function and structure without them. However, it is well known that these components cause…
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Keywords:
protein dna;
non volatile;
dna complexes;
mass spectrometry ... See more keywords
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Published in 2017 at "Molecular bioSystems"
DOI: 10.1039/c7mb00071e
Abstract: The lifetimes of protein-DNA adducts are strictly related to the various protein functions. This feature must be encoded by the amino acids located at the protein-DNA interface. The large number of structurally characterized protein-DNA complexes…
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Keywords:
dna;
protein dna;
dna complexes;
contact ... See more keywords
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Published in 2025 at "Glycobiology"
DOI: 10.1093/glycob/cwaf070
Abstract: Although the interaction between β-1,3-glucans (BG) and β-1,3-glucan recognition protein (BGRP) derived from insects is well established, the binding interaction and recognition mechanism of BG when complexed with deoxyadenosine (dA) or CpG oligodeoxynucleotides (CpG) remain…
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Keywords:
recognition protein;
recognition;
bgrp;
glucan recognition ... See more keywords
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1
Published in 2022 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkac774
Abstract: Abstract The introduction of phosphorothioate (PS) linkages to the backbone of therapeutic nucleic acids substantially increases their stability and potency. It also affects their interactions with cellular proteins, but the molecular mechanisms that underlie this…
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Keywords:
annexin dna;
dna;
complexes show;
dna complexes ... See more keywords
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Published in 2017 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkw1049
Abstract: The single-step assembly of supramolecular complexes containing both i-motifs and G-quadruplexes (G4s) is demonstrated. This can be achieved because the formation of four-stranded i-motifs appears to be little affected by certain terminal residues: a five-cytosine…
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Keywords:
quadruplexes motifs;
supramolecular dna;
assembly supramolecular;
dna complexes ... See more keywords
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Published in 2022 at "Rheumatology"
DOI: 10.1093/rheumatology/keac192
Abstract: OBJECTIVE Leucocyte immunoglobulin-like receptor A3 (LILRA3) belongs to a family of leucocyte receptors. Our previous study reported LILRA3 transcripts were markedly upregulated in neutrophils from patients with antiphospholipid syndrome (APS). We undertook this study to…
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Keywords:
lilra3;
mpo dna;
dna complexes;
antiphospholipid syndrome ... See more keywords