Articles with "dna ctdna" as a keyword



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Clinical factors associated with circulating tumor DNA (ctDNA) in primary breast cancer

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Published in 2019 at "Molecular Oncology"

DOI: 10.1002/1878-0261.12456

Abstract: Noninvasive circulating tumor DNA (ctDNA) can be used to predict breast cancer recurrence and prognosis. In this study, we detected 226 and 114 somatic variants in tumor DNA from 70 primary breast cancer (PBC) patients… read more here.

Keywords: dna ctdna; breast cancer; tumor dna; tumor ... See more keywords
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Abstract C012:Real-worlduse of circulating tumor DNA (ctDNA) in the clinical management of patients with solid tumors: A single institution’s experience

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Published in 2019 at "Molecular Cancer Therapeutics"

DOI: 10.1158/1535-7163.targ-19-c012

Abstract: Background: The analysis of circulating tumor DNA (ctDNA) is becoming an instrumental tool in the practice of precision oncology. It not only provides a non-invasive method to study the mutational composition of solid tumors, particularly… read more here.

Keywords: clinical management; dna ctdna; cancer; tumor dna ... See more keywords
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Study of circulating tumor DNA (ctDNA) of RAS-wild metastatic colorectal cancer (mCRC) as a tool for on-site mutation screening: A prospective study.

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Published in 2017 at "Journal of Clinical Oncology"

DOI: 10.1200/jco.2017.35.15_suppl.e15077

Abstract: e15077Background: Clinical use of ctDNA has been become an important criterion for patient care. The transfer of this knowledge and technology from top clinical labs to local hospitals is still dis... read more here.

Keywords: ctdna ras; dna ctdna; study; circulating tumor ... See more keywords
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Cell free circulating tumor DNA (ctDNA) landscape in patients with advanced gastroesophageal adenocarcinoma (GEC).

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Published in 2017 at "Journal of Clinical Oncology"

DOI: 10.1200/jco.2017.35.4_suppl.47

Abstract: 47Background: Esophageal (EC), gastroesophageal junction (GEJ) and gastric cancer (GC), together GEC, have a poor prognosis with few targeted therapeutic options. As genomic profiling is becoming increasingly useful, we queried whether comprehensive genomic profiling of… read more here.

Keywords: ctdna; dna ctdna; cell free; circulating tumor ... See more keywords
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Circulating tumor DNA (ctDNA) in patients (pts) with metastatic uveal melanoma (UM) treated with protein kinase C inhibitor (PKCi).

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Published in 2020 at "Journal of Clinical Oncology"

DOI: 10.1200/jco.2020.38.15_suppl.e22054

Abstract: e22054Background: UM is the most common primary intraocular malignancy. About 50% of pts with UM will develop metastatic disease and currently there is no effective treatment in metastatic UM. Near... read more here.

Keywords: pts metastatic; dna ctdna; ctdna patients; circulating tumor ... See more keywords
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Prognostic and predictive value of circulating tumour DNA (ctDNA) by amplicon-based next generation sequencing (NGS) of advanced pancreatic cancer (APC) in a phase I trial of oxaliplatin capecitabine and irinotecan (OXIRI) triplet chemotherapy.

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Published in 2020 at "Journal of Clinical Oncology"

DOI: 10.1200/jco.2020.38.4_suppl.730

Abstract: 730Background: Tumoral KRAS mutations (KRASmt) are detected in ~80% of APC and associated with a negative prognosis. Digital droplet PCR (ddPCR) has high sensitivity for circulating KRASmtbut narro... read more here.

Keywords: value circulating; dna ctdna; tumour dna; prognostic predictive ... See more keywords
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Comparative circulating tumor DNA (ctDNA) genomic profiling in 110 patients with advanced renal cell carcinoma.

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Published in 2020 at "Journal of Clinical Oncology"

DOI: 10.1200/jco.2020.38.6_suppl.743

Abstract: 743Background: Circulating tumor DNA (ctDNA) profiling is a non-invasive method to genomically assess solid tumors. Key benchmarks are required to assess applications in RCC management. To evaluate... read more here.

Keywords: dna ctdna; circulating tumor; tumor dna;
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Usefulness of assessment of circulating tumor DNA(ctDNA) of cerebrospinal fluid(CSF) samples for early detection of brain metastasis (BrM) in patients with triple-negative breast cancer (TNBC).

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Published in 2021 at "Journal of Clinical Oncology"

DOI: 10.1200/jco.2021.39.15_suppl.507

Abstract: 507Background: Despite improvements in treatments, patients diagnosed with TNBC still have poor prognosis for a higher tendency of developing BrM. Identifying patients at high risk of BrM, enabling... read more here.

Keywords: assessment circulating; usefulness assessment; dna ctdna; tumor dna ... See more keywords
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Baseline Plasma Tumor DNA (ctDNA) Correlates with PSA Kinetics in Metastatic Castration-Resistant Prostate Cancer (mCRPC) Treated with Abiraterone or Enzalutamide

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Published in 2022 at "Cancers"

DOI: 10.3390/cancers14092219

Abstract: Simple Summary Prostate cancer is a very common disease in men. Nowadays several life-prolonging therapies are available, also efficient in the metastatic setting. However, it is important to choose the best approach for each patient,… read more here.

Keywords: dna ctdna; ctdna; treated abiraterone; gain ... See more keywords