Charge-Shifting Polycations Based on N,N-(dimethylamino)ethyl Acrylate for Improving Cytocompatibility During DNA Delivery
Sign Up to like & getrecommendations! Published in 2020 at "ACS Omega"
DOI: 10.1021/acsomega.9b03734
Abstract: Synthetic polycations are studied extensively as DNA delivery agents because of their ease of production, good chemical stability, and low cost relative to viral vectors. This report describes the synthesis of charge-shifting polycations based on… read more here.
Keywords: charge shifting; shifting polycations; dna delivery; charge ... See more keywords
Endosome-escaping micelle complexes dually equipped with cell-penetrating and endosome-disrupting peptides for efficient DNA delivery into intact plants.
Sign Up to like & getrecommendations! Published in 2021 at "Nanoscale"
DOI: 10.1039/d0nr08183c
Abstract: The delivery of DNA to plants is crucial for enhancing their ability to produce valuable compounds and adapt to climate change. Peptides can provide a versatile tool for delivering DNA to a specific target organelle… read more here.
Keywords: escaping micelle; dna; delivery; cell penetrating ... See more keywords
Optimization of precision nanofiber micelleplexes for DNA delivery.
Sign Up to like & getrecommendations! Published in 2023 at "Biomaterials science"
DOI: 10.1039/d2bm02014a
Abstract: As nucleic acid (NA) technologies continue to revolutionize medicine, new delivery vehicles are needed to effectively transport NA cargoes into cells. Uniform and length-tunable nanofiber micelleplexes have recently shown promise as versatile polymeric delivery vehicles… read more here.
Keywords: optimization precision; precision nanofiber; nanofiber micelleplexes; micelleplexes dna ... See more keywords
Peptide-Based Nanoparticles for αvβ3 Integrin-Targeted DNA Delivery to Cancer and Uterine Leiomyoma Cells
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DOI: 10.3390/molecules27238363
Abstract: Uterine leiomyoma is the most common benign tumor of the reproductive system. Current therapeutic options do not simultaneously meet the requirements of long-term efficiency and fertility preservation. Suicide gene delivery can be proposed as a… read more here.
Keywords: peptide based; uterine leiomyoma; leiomyoma; dna delivery ... See more keywords
Chitosan-Crosslinked Low Molecular Weight PEI-Conjugated Iron Oxide Nanoparticle for Safe and Effective DNA Delivery to Breast Cancer Cells
Sign Up to like & getrecommendations! Published in 2022 at "Nanomaterials"
DOI: 10.3390/nano12040584
Abstract: Breast cancer has attracted tremendous research interest in treatment development as one of the major threats to public health. The use of non-viral carriers for therapeutic DNA delivery has shown promise in treating various cancer… read more here.
Keywords: dna; nanoparticle; breast cancer; dna delivery ... See more keywords