Wavelength-Dependent, Orthogonal Photoregulation of DNA Liberation for Logic Operations.
Sign Up to like & getrecommendations! Published in 2022 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.2c20757
Abstract: In this study, we synthesized two phosphoramidites based on 2,7-bis-{4-nitro-8-[3-(2-propyl)-styryl]}-9,9-bis-[1-(3,6-dioxaheptyl)]-fluorene (BNSF) and 4,4'-bis-{8-[4-nitro-3-(2-propyl)-styryl]}-3,3'-di-methoxybiphenyl (BNSMB) structures as visible light-cleavable linkers for oligonucleotide conjugation. In addition to the commercial ultraviolet (UV) photocleavable (PC) linker, the BNSMB linker… read more here.
Keywords: dna; orthogonal photoregulation; wavelength dependent; dependent orthogonal ... See more keywords
Detecting Attomolar DNA-Damaging Anticancer Drug Activity in Cell Lysates with Electrochemical DNA Devices.
Sign Up to like & getrecommendations! Published in 2021 at "ACS sensors"
DOI: 10.1021/acssensors.1c00365
Abstract: Here, we utilize electrochemical DNA devices to quantify and understand the cancer-specific DNA-damaging activity of an emerging drug in cellular lysates at femtomolar and attomolar concentrations. Isobutyl-deoxynyboquinone (IB-DNQ), a potent and tumor-selective NAD(P)H quinone oxidoreductase… read more here.
Keywords: dna devices; dna damaging; dna; electrochemical dna ... See more keywords
Reconfigurable self-assembled DNA devices
Sign Up to like & getrecommendations! Published in 2023 at "Science Robotics"
DOI: 10.1126/scirobotics.adh8148
Abstract: Modular reconfigurable systems can be achieved with DNA origami, demonstrating the potential to generate molecular robots. Description Modular reconfigurable systems can be achieved with DNA origami, demonstrating the potential to generate molecular robots. read more here.
Keywords: dna devices; reconfigurable self; self assembled; assembled dna ... See more keywords