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Published in 2020 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-9865-4_8
Abstract: cis-regulatory DNA elements (CREs) are noncoding but functional DNA sequences. The binding of regulatory proteins into CRE regions leads to chromatin high sensitive to DNase I digestion, which are termed as DNase I hypersensitive sites…
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Keywords:
dnase;
regulatory dna;
dnase seq;
dna elements ... See more keywords
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Published in 2020 at "Nature"
DOI: 10.1038/s41586-020-2493-4
Abstract: The human and mouse genomes contain instructions that specify RNAs and proteins and govern the timing, magnitude, and cellular context of their production. To better delineate these elements, phase III of the Encyclopedia of DNA…
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Keywords:
mouse genomes;
human mouse;
expanded encyclopaedias;
encyclopaedias dna ... See more keywords
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Published in 2018 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkx1081
Abstract: Abstract The Encyclopedia of DNA Elements (ENCODE) Data Coordinating Center has developed the ENCODE Portal database and website as the source for the data and metadata generated by the ENCODE Consortium. Two principles have motivated…
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Keywords:
encyclopedia dna;
elements encode;
encode data;
dna elements ... See more keywords
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Published in 2019 at "Genome Biology"
DOI: 10.1186/s13059-019-1722-3
Abstract: BackgroundThe three-dimensional (3D) organization of chromosomes is linked to epigenetic regulation and transcriptional activity. However, only few functional features of 3D chromatin architecture have been described to date. The KNOT is a 3D chromatin structure…
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Keywords:
knot;
invasive dna;
biology;
dna elements ... See more keywords
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Published in 2022 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2022.827545
Abstract: Klebsiella pneumoniae exhibits extensive phenotypic and genetic diversity. Higher plasmid loads in the cell were supposed to play an key role in its genome diversity. Although some plasmids are widely distributed in Kp populations, they…
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Keywords:
dna elements;
klebsiella pneumoniae;
phage;
virulence ... See more keywords