Alternative Mechanisms for DNA Engagement by BET Bromodomain-Containing Proteins.
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DOI: 10.1021/acs.biochem.2c00157
Abstract: Epigenetic reader domains regulate chromatin structure and modulate gene expression through the recognition of post-translational modifications on histones. Recently, reader domains have also been found to harbor double-stranded (ds) DNA-binding activity, which is as functionally… read more here.
Keywords: dna engagement; bet; mechanisms dna; bet bromodomain ... See more keywords