Minicircle DNA-Engineered CAR T Cells Suppressed Tumor Growth in Mice
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DOI: 10.1158/1535-7163.mct-19-0204
Abstract: Viral-based chimeric antigen receptor-engineered T (CAR T)–cell manufacturing has potential safety risks and relatively high costs. The nonviral minicircle DNA (mcDNA) is safer for patients, cheaper to produce, and may be a more suitable technique… read more here.
Keywords: car cells; dna engineered; minicircle dna; engineered car ... See more keywords