How chromosome topologies get their shape: views from proximity ligation and microscopy methods
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DOI: 10.1002/1873-3468.13961
Abstract: The 3D organization of our genome is an important determinant for the transcriptional output of a gene in (patho)physiological contexts. The spatial organization of linear chromosomes within nucleus is dominantly inferred using two distinct approaches,… read more here.
Keywords: proximity ligation; microscopy; ligation; dna fish ... See more keywords