Recent Progress of Triplex DNA Formation and Its Applications.
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DOI: 10.1021/acs.jmedchem.4c02518
Abstract: Recently, much attention has been focused on oligonucleotide drugs that precisely control the gene expression. Among these, triplex-forming oligonucleotides (TFOs) represent common antigene strategies because they bind specifically to the major groove position of genomic… read more here.
Keywords: progress triplex; recent progress; dna formation; triplex dna ... See more keywords
Contrasting effects of mismatch locations on Z-DNA formation under bending force
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DOI: 10.1039/d5sc00749f
Abstract: Z-DNA is a non-canonical, left-handed helical structure that plays crucial roles in various cellular processes. DNA mismatches, which involve the incorporation of incorrect Watson–Crick base pairs, are present in all living organisms and contribute to… read more here.
Keywords: dna formation; bending force; formation; formation bending ... See more keywords