Extension of hydrodynamic chromatography to DNA fragment sizing and quantitation
Sign Up to like & getrecommendations! Published in 2021 at "Heliyon"
DOI: 10.1016/j.heliyon.2021.e07904
Abstract: Hydrodynamic chromatography (HDC) is a technique originally developed for separating particles. We have recently extended it to DNA fragment sizing and quantitation. In this review, we focus on this extension. After we briefly introduce the… read more here.
Keywords: sizing quantitation; hydrodynamic chromatography; fragment sizing; dna fragment ... See more keywords
An efficient method for the construction of artificial, concatemeric DNA, RNA and proteins with genetically programmed functions, using a novel, vector-enzymatic DNA fragment amplification-expression technology
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DOI: 10.1016/j.mex.2020.101070
Abstract: De novo designed bioactive molecules, such as DNA, RNA and peptides, are utilized in increasingly diverse scientific, industrial and biomedical applications. Concatemerization of designed DNA, RNA and peptides may improve their stability, bioactivity and allow… read more here.
Keywords: dna; enzymatic dna; dna fragment; dna rna ... See more keywords
Duplication with structural modification through extrachromosomal circular and lariat DNA in the human genome
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DOI: 10.1038/s41598-020-63665-6
Abstract: Duplication plays an important role in creating drastic changes in genome evolution. In addition to well-known tandem duplication, duplication can occur such that a duplicated DNA fragment is inserted at another location in the genome.… read more here.
Keywords: structural modification; dna fragment; duplication; dna ... See more keywords
Shedding light on dark genes: enhanced targeted resequencing by optimizing the combination of enrichment technology and DNA fragment length
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DOI: 10.1038/s41598-020-66331-z
Abstract: The exome contains many obscure regions difficult to explore with current short-read sequencing methods. Repetitious genomic regions prevent the unique alignment of reads, which is essential for the identification of clinically-relevant genetic variants. Long-read technologies… read more here.
Keywords: dna fragment; dna; obscure regions; shedding light ... See more keywords