Rapid and Selective Determination of Zika Virus RNA using a Universal DNA-Hairpin probe.
Sign Up to like & getrecommendations! Published in 2019 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.9b02455
Abstract: The recent outbreak of the Zika virus (ZIKV) in the Americas and multiple studies that linked the virus to the cases of microcephaly and neurological complications have revealed the need for cost efficient and rapid… read more here.
Keywords: probe; dna; zikv; dna hairpin ... See more keywords
Duplex DNA is Weakened in Nanoconfinement.
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DOI: 10.1021/jacs.0c01978
Abstract: For proteins and DNA secondary structures such as G-quadruplexes and i-motifs, nanoconfinement can facilitate their folding and increase structural stabilities. However, properties of physiologically prevalent B-DNA duplex have not been elucidated inside nanocavity. By using… read more here.
Keywords: dna; duplex; hairpin dna; dna hairpin ... See more keywords
Programming chain-growth copolymerization of DNA hairpin tiles for in-vitro hierarchical supramolecular organization
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DOI: 10.1038/s41467-019-09004-4
Abstract: Formation of biological filaments via intracellular supramolecular polymerization of proteins or protein/nucleic acid complexes is under programmable and spatiotemporal control to maintain cellular and genomic integrity. Here we devise a bioinspired, catassembly-like isothermal chain-growth approach… read more here.
Keywords: chain growth; chain; hairpin tiles; dna hairpin ... See more keywords
Liquid-liquid phase separation rescues the conformational stability of a DNA hairpin from pressure-stress.
Sign Up to like & getrecommendations! Published in 2019 at "Chemical communications"
DOI: 10.1039/c9cc04967c
Abstract: We used single-molecule FRET experiments to monitor the conformational equilibrium of a DNA hairpin under pressure-stress in the presence of an aqueous two-phase system mimicking intracellular liquid-liquid phase separation (LLPS). Our data demonstrate the important… read more here.
Keywords: phase; liquid; hairpin pressure; pressure stress ... See more keywords