Human DNA helicase, RuvBL1 and its Chlamydomonas homologue, CrRuvBL1 plays an important role in ciliogenesis
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DOI: 10.1002/cm.21377
Abstract: Several nuclear and nucleic acid‐binding proteins were detected in the proteomic analyses of ciliary fractions from various organisms. Yet very little is known about the role of these proteins in ciliogenesis and ciliary signaling. In… read more here.
Keywords: dna helicase; human dna; important role; role ciliogenesis ... See more keywords
Tau Pathology Associated With Parkinsonism and Mutation of Mitochondrial DNA Helicase Gene TWNK
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DOI: 10.1212/nxg.0000000000000620
Abstract: The TWNK gene encodes Twinkle, the mitochondrial DNA helicase that cooperates with the mitochondrial DNA polymerase (POLG) to maintain mitochondrial DNA integrity. Heterozygous TWNK mutations cause autosomal dominant progressive external ophthalmoplegia (PEO). Some patients with… read more here.
Keywords: pathology; gene; parkinsonism; mitochondrial dna ... See more keywords