Oncogene Convergence in Extrachromosomal DNA Hubs
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DOI: 10.1158/2159-8290.cd-22-0076
Abstract: Summary: Extrachromosomal DNA circles (ecDNA) are a common mechanism for oncogene amplification and are associated with worse clinical outcomes compared with other types of oncogene amplification. Several recent discoveries of ecDNA hubs—local congregations of ecDNAs… read more here.
Keywords: convergence extrachromosomal; dna; dna hubs; oncogene convergence ... See more keywords