Microfluidic Arrayed Lab-On-A-Chip for Electrochemical Capacitive Detection of DNA Hybridization Events.
Sign Up to like & getrecommendations! Published in 2017 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-6911-1_6
Abstract: A microfluidic electrochemical lab-on-a-chip (LOC) device for DNA hybridization detection has been developed. The device comprises a 3 × 3 array of microelectrodes integrated with a dual layer microfluidic valved manipulation system that provides controlled and automated… read more here.
Keywords: detection; dna; hybridization; dna hybridization ... See more keywords
Influence of graphene’s chemical potential on SPR biosensor using ZnO for DNA hybridization
Sign Up to like & getrecommendations! Published in 2019 at "Optical Review"
DOI: 10.1007/s10043-019-00564-w
Abstract: This article presents an SPR biosensor (Structure: SF10 prism-Au-ZnO-Graphene-PBS solution) to sense DNA hybridization using angular interrogation method at an operating wavelength of 633 nm. Its performance parameters, i.e., sensitivity ( S ), detection accuracy (DA),… read more here.
Keywords: dna hybridization; spr biosensor; chemical potential; graphene chemical ... See more keywords
Magnetic Beads Compatibility as DNA Hybridization Labels in Integrated Thermal-Magnetic Biosensor
Sign Up to like & getrecommendations! Published in 2017 at "BioNanoScience"
DOI: 10.1007/s12668-017-0410-6
Abstract: In this paper, we investigated the applicative using of thermal-magnetic biosensor (TMAGS) for DNA detection. TMAGS is a planar device composed by a primary microcoil able to generate a magnetic field which induces a voltage… read more here.
Keywords: compatibility; hybridization; dna hybridization; magnetic biosensor ... See more keywords
Magnetic beads-based DNA hybridization chain reaction amplification and DNAzyme recognition for colorimetric detection of uranyl ion in seafood.
Sign Up to like & getrecommendations! Published in 2017 at "Analytica chimica acta"
DOI: 10.1016/j.aca.2016.12.021
Abstract: A novel colorimetric biosensor, which employs DNAzyme-functionalized magnetic beads (MBs) as recognition probe, enzyme-assisted catalytic oxidation of TMB (3,3',5,5'-tetramethylbenzidine sulfate) as signal and DNA hybridization chain reaction as amplification strategy, has been developed for detecting… read more here.
Keywords: dna hybridization; hybridization chain; chain reaction;
Thermodynamic analysis of DNA hybridization signatures near mitochondrial DNA deletion breakpoints
Sign Up to like & getrecommendations! Published in 2021 at "iScience"
DOI: 10.1016/j.isci.2021.102138
Abstract: Summary Broad evidence in the literature supports double-strand breaks (DSBs) as initiators of mitochondrial DNA (mtDNA) deletion mutations. While DNA misalignment during DSB repair is commonly proposed as the mechanism by which DSBs cause deletion… read more here.
Keywords: dna; analysis; deletion; mtdna deletion ... See more keywords
Light-Amplified CISS-Based Hybrid QD-DNA Impedimetric Device for DNA Hybridization Detection.
Sign Up to like & getrecommendations! Published in 2023 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.2c04608
Abstract: We design and build a novel light-amplified electrochemical impedimetric device based on the CISS effect to detect DNA hybridization using a hybrid quantum dot (QD)-DNA monolayer on a ferromagnetic (FM) Ni/Au thin film for the… read more here.
Keywords: impedimetric device; detection; dna hybridization; dna ... See more keywords
Miniature Hierarchical DNA Hybridization Circuit for Amplified Multiplexed MicroRNA Imaging.
Sign Up to like & getrecommendations! Published in 2023 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.2c05373
Abstract: Accurate diagnosis requires the development of multiple-guaranteed DNA circuits. Nevertheless, for reliable multiplexed molecular imaging, existing DNA circuits are limited by poor cell-delivering homogeneity due to their cumbersome and dispersive reactants. Herein, we developed a… read more here.
Keywords: dna; circuit; hdh circuit; dna hybridization ... See more keywords
Graphene Oxide-Functionalized Thread-Based Electrofluidic Approach for DNA Hybridization
Sign Up to like & getrecommendations! Published in 2023 at "ACS Omega"
DOI: 10.1021/acsomega.2c06228
Abstract: A novel, low-cost, and disposable thread-based electrofluidic analytical method employing isotachophoresis (ITP) was developed for demonstrating surface DNA hybridization. This approach was based on graphene oxide (GO) surface-functionalized zones on nylon threads as a binding… read more here.
Keywords: dna; dna hybridization; hybridization; thread based ... See more keywords
Gold Nanoparticle-Bridge Array to Improve DNA Hybridization Efficiency of SERS Sensors.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.2c06623
Abstract: The interfacial mass transfer rate of a target has a significant impact on the sensing performance. The surface reaction forms a concentration gradient perpendicular to the surface, wherein a slow mass transfer process decreases the… read more here.
Keywords: bridge array; dna hybridization; array; efficiency ... See more keywords
5-Methyl-cytosine stabilizes DNA but hinders DNA hybridization revealed by magnetic tweezers and simulations
Sign Up to like & getrecommendations! Published in 2022 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkac1122
Abstract: Abstract 5-Methyl-cytosine (5mC) is one of the most important DNA modifications and plays versatile biological roles. It is well known that 5mC stabilizes DNA duplexes. However, it remains unclear how 5mC affects the kinetics of… read more here.
Keywords: methyl cytosine; stabilizes dna; dna hybridization; hybridization ... See more keywords
The stability and number of nucleating interactions determine DNA hybridization rates in the absence of secondary structure
Sign Up to like & getrecommendations! Published in 2022 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkac590
Abstract: Abstract The kinetics of DNA hybridization are fundamental to biological processes and DNA-based technologies. However, the precise physical mechanisms that determine why different DNA sequences hybridize at different rates are not well understood. Secondary structure… read more here.
Keywords: dna hybridization; secondary structure; hybridization rates; hybridization ... See more keywords