DNA hypomethylation promotes invasion and metastasis of gastric cancer cells by regulating the binding of SP1 to the CDCA3 promoter
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.28993
Abstract: Cell division cycle associated protein‐3 (CDCA3) has been reported frequently upregulated in various cancers. It has been progressively realized that changed DNA methylations occur in diverse carcinomas. However, the concrete involvement of CDCA3 and DNA… read more here.
Keywords: dna; gastric cancer; cdca3; dna hypomethylation ... See more keywords
Global DNA hypomethylation has no impact on lung function or serum inflammatory and fibrosis cytokines in asbestos-exposed population
Sign Up to like & getrecommendations! Published in 2017 at "International Archives of Occupational and Environmental Health"
DOI: 10.1007/s00420-017-1195-1
Abstract: PurposeTo examine the effect of asbestos exposure on global DNA methylation and determine whether lung function and inflammatory and fibrosis biomarkers are correlated with the methylation state.MethodsA total of 26 healthy subjects without asbestos exposure… read more here.
Keywords: function; dna hypomethylation; global dna; lung function ... See more keywords
Toxicological effects of atenolol and venlafaxine on zebrafish tissues: Bioaccumulation, DNA hypomethylation, and molecular mechanism.
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DOI: 10.1016/j.envpol.2022.118898
Abstract: The beta-blocker atenolol (ATE), and the selective serotonin and norepinephrine reuptake inhibitor, venlafaxine (VEN) are frequently detected in municipal wastewater effluents, but little is known about their ecotoxic effect on aquatic animals. Herein, ATE and… read more here.
Keywords: dna; zebrafish tissues; ate ven; dna hypomethylation ... See more keywords
S100P Expression via DNA Hypomethylation Promotes Cell Growth in the Sessile Serrated Adenoma/Polyp-Cancer Sequence
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DOI: 10.1159/000512575
Abstract: Background/Aims: Sessile serrated adenomas/polyps (SSA/Ps) are a putative precursor lesion of colon cancer. Although the relevance of DNA hypermethylation in the SSA/P-cancer sequence is well documented, the role of DNA hypomethylation is unknown. We investigated… read more here.
Keywords: ssa; cancer sequence; hypomethylation; cancer ... See more keywords
Genome-wide DNA hypomethylation drives a more invasive pancreatic cancer phenotype and has predictive occult distant metastasis and prognosis potential
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Oncology"
DOI: 10.3892/ijo.2022.5351
Abstract: Genome-wide DNA hypomethylation is the most common molecular feature in human cancers associated with chromosomal instability (CIN), which is involved in the mechanisms that regulate pancreatic cancer (PC) metastasis. It was investigated whether genome-wide DNA… read more here.
Keywords: dna hypomethylation; dna; metastasis; wide dna ... See more keywords