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Published in 2018 at "Nature Communications"
DOI: 10.1038/s41467-018-06771-4
Abstract: Oncolytic virotherapy is a promising therapeutic strategy that uses replication-competent viruses to selectively destroy malignancies. However, the therapeutic effect of certain oncolytic viruses (OVs) varies among cancer patients. Thus, it is necessary to overcome resistance…
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Keywords:
cancer;
dna inhibition;
antiviral response;
dna ... See more keywords
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Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.15062
Abstract: During DNA double strand breaks (DSBs) repair, coordinated activation of phosphatidylinositol 3-kinase (PI3K)-like kinases can activate p53 signaling pathway. Recent findings have identified novel interplays among these kinases demonstrating amplified first p53 pulses under DNA-PK…
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Keywords:
amplified p53;
inhibition;
dna inhibition;
p53 responses ... See more keywords