Articles with "dna integrity" as a keyword



Deterioration of semen quality and sperm‐DNA integrity as influenced by cigarette smoking in fertile and infertile human male smokers—A prospective study

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Published in 2019 at "Journal of Cellular Biochemistry"

DOI: 10.1002/jcb.28458

Abstract: In modernized lifestyle smoking is one of the trendy, psychological, and socioeconomic scenarios of young adolescents mainly in the age of the reproductive stage. Based on a number of cigarettes smoked, age, and duration of… read more here.

Keywords: sperm dna; study; fertile infertile; infertile ... See more keywords

Circulating cell-free DNA integrity as a diagnostic and prognostic marker for breast and prostate cancers.

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Published in 2019 at "Cancer genetics"

DOI: 10.1016/j.cancergen.2019.04.062

Abstract: BACKGROUND Cancer incidence and its related mortality is rising and is currently the second leading cause of death globally. In Africa, breast and prostate cancer in females and males, respectively, are the worst globally. However,… read more here.

Keywords: dna; prostate; cancer; breast ... See more keywords

Use of sperm DNA integrity as a marker for exposure to contamination in Palaemon serratus (Pennant 1777): Intrinsic variability, baseline level and in situ deployment.

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Published in 2018 at "Water research"

DOI: 10.1016/j.watres.2017.12.057

Abstract: In a previous study, the Comet assay was optimized for Palaemon serratus prawns in order to propose a biomarker for sperm quality in this species. However, better knowledge of its basal level and its natural… read more here.

Keywords: level; variability; contamination; dna integrity ... See more keywords

A straightforward assay to evaluate DNA integrity and optimize next-generation sequencing for clinical diagnosis in oncology.

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Published in 2017 at "Experimental and molecular pathology"

DOI: 10.1016/j.yexmp.2017.11.011

Abstract: Next generation sequencing (NGS) has become an informative tool to guide cancer treatment and conduce a personalized approach in oncology. The biopsy collected for pathologic analysis is usually stored as formalin-fixed paraffin-embedded (FFPE) blocks and… read more here.

Keywords: dna; next generation; dna integrity; oncology ... See more keywords

The association between age-related infertility and deoxyribonucleic acid (DNA) integrity parameters of granulosa cells and lymphocytes

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Published in 2022 at "Journal of Obstetrics and Gynaecology"

DOI: 10.1080/01443615.2022.2054689

Abstract: Abstract This study aimed to investigate the association between deoxyribonucleic acid (DNA) integrity parameters and advanced maternal age (AMA)-related infertility. The granulosa cells and the lymphocytes obtained from 119 infertile women were recruited. Patients were… read more here.

Keywords: ama group; dna integrity; integrity parameters;

Sperm DNA Integrity is Unaffected by Thiopurine Treatment in Men With Inflammatory Bowel Disease

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Published in 2019 at "Journal of Crohn's and Colitis"

DOI: 10.1093/ecco-jcc/jjy086

Abstract: Background and Aims Sperm DNA integrity, concentration, and motility are suspected to be altered by thiopurines (azathioprine [AZA] and 6-mercaptopurine [6-MP]). We investigated the impact of thiopurines on semen quality in men with inflammatory bowel… read more here.

Keywords: bowel disease; dna; inflammatory bowel; sperm dna ... See more keywords

P-039 Enhancing Male Fertility: The Impact of Targeted Nutraceutical Supplementation on Sperm Quality, DNA Integrity and Pregnancy Outcome

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Published in 2025 at "Human Reproduction"

DOI: 10.1093/humrep/deaf097.348

Abstract: Can a Targeted nutraceutical supplementation improve semen parameters and enhance the chances of pregnancy in female partners? A three-month targeted nutraceutical regimen improved semen quality and sperm DNA integrity, leading to improvements in pregnancy outcomes,… read more here.

Keywords: supplementation; targeted nutraceutical; dna integrity; dna ... See more keywords

P-075 Microplastic exposure impairs human sperm motility and DNA integrity via oxidative stress

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Published in 2025 at "Human Reproduction"

DOI: 10.1093/humrep/deaf097.384

Abstract: Does exposure to Polyvinyl Chloride (PVC) adversely affect human sperm motility, oxidative stress levels, and DNA integrity? PVC exposure significantly reduces sperm motility, increases reactive oxygen species (ROS) levels, and induces sperm DNA damage in… read more here.

Keywords: motility; oxidative stress; dna integrity; sperm motility ... See more keywords

Normal Sperm DNA Integrity in Patients With Inflammatory Bowel Disease on Ustekinumab Maintenance Therapy.

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Published in 2022 at "Inflammatory bowel diseases"

DOI: 10.1093/ibd/izac028

Abstract: We demonstrate that ustekinumab does not adversely affect semen quality or sex hormones in male patients. Ustekinumab is not detectable in semen and poses no risk to partners. Our observations support a recommendation to continue… read more here.

Keywords: dna integrity; integrity patients; sperm dna; inflammatory bowel ... See more keywords

Supplementation of quercetin for advanced DNA integrity in bull semen cryopreservation

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Published in 2018 at "Andrologia"

DOI: 10.1111/and.12975

Abstract: The aim of this study was to identify the effects of adding quercetin (Q) to Tris extender in order to identify levels of oxidative stress in bull sperm after freeze thawing. Ejaculates were collected via… read more here.

Keywords: bull; supplementation; tris extender; integrity ... See more keywords

How defective spermatogenesis affects sperm DNA integrity

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Published in 2020 at "Andrologia"

DOI: 10.1111/and.13615

Abstract: Spermatogenesis is the essential process to maintain and promote male fertility. It is extraordinarily complex with many regulatory elements and numerous steps. The process involves several cell types, regulatory molecules, repair mechanisms and epigenetic regulators.… read more here.

Keywords: spermatogenesis; sperm dna; defective spermatogenesis; spermatogenesis affects ... See more keywords