Deterioration of semen quality and sperm‐DNA integrity as influenced by cigarette smoking in fertile and infertile human male smokers—A prospective study
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.28458
Abstract: In modernized lifestyle smoking is one of the trendy, psychological, and socioeconomic scenarios of young adolescents mainly in the age of the reproductive stage. Based on a number of cigarettes smoked, age, and duration of… read more here.
Keywords: sperm dna; study; fertile infertile; infertile ... See more keywords
Circulating cell-free DNA integrity as a diagnostic and prognostic marker for breast and prostate cancers.
Sign Up to like & getrecommendations! Published in 2019 at "Cancer genetics"
DOI: 10.1016/j.cancergen.2019.04.062
Abstract: BACKGROUND Cancer incidence and its related mortality is rising and is currently the second leading cause of death globally. In Africa, breast and prostate cancer in females and males, respectively, are the worst globally. However,… read more here.
Keywords: dna; prostate; cancer; breast ... See more keywords
Use of sperm DNA integrity as a marker for exposure to contamination in Palaemon serratus (Pennant 1777): Intrinsic variability, baseline level and in situ deployment.
Sign Up to like & getrecommendations! Published in 2018 at "Water research"
DOI: 10.1016/j.watres.2017.12.057
Abstract: In a previous study, the Comet assay was optimized for Palaemon serratus prawns in order to propose a biomarker for sperm quality in this species. However, better knowledge of its basal level and its natural… read more here.
Keywords: level; variability; contamination; dna integrity ... See more keywords
A straightforward assay to evaluate DNA integrity and optimize next-generation sequencing for clinical diagnosis in oncology.
Sign Up to like & getrecommendations! Published in 2017 at "Experimental and molecular pathology"
DOI: 10.1016/j.yexmp.2017.11.011
Abstract: Next generation sequencing (NGS) has become an informative tool to guide cancer treatment and conduce a personalized approach in oncology. The biopsy collected for pathologic analysis is usually stored as formalin-fixed paraffin-embedded (FFPE) blocks and… read more here.
Keywords: dna; next generation; dna integrity; oncology ... See more keywords
The association between age-related infertility and deoxyribonucleic acid (DNA) integrity parameters of granulosa cells and lymphocytes
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Obstetrics and Gynaecology"
DOI: 10.1080/01443615.2022.2054689
Abstract: Abstract This study aimed to investigate the association between deoxyribonucleic acid (DNA) integrity parameters and advanced maternal age (AMA)-related infertility. The granulosa cells and the lymphocytes obtained from 119 infertile women were recruited. Patients were… read more here.
Keywords: ama group; dna integrity; integrity parameters;
Sperm DNA Integrity is Unaffected by Thiopurine Treatment in Men With Inflammatory Bowel Disease
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Crohn's and Colitis"
DOI: 10.1093/ecco-jcc/jjy086
Abstract: Background and Aims Sperm DNA integrity, concentration, and motility are suspected to be altered by thiopurines (azathioprine [AZA] and 6-mercaptopurine [6-MP]). We investigated the impact of thiopurines on semen quality in men with inflammatory bowel… read more here.
Keywords: bowel disease; dna; inflammatory bowel; sperm dna ... See more keywords
Normal Sperm DNA Integrity in Patients With Inflammatory Bowel Disease on Ustekinumab Maintenance Therapy.
Sign Up to like & getrecommendations! Published in 2022 at "Inflammatory bowel diseases"
DOI: 10.1093/ibd/izac028
Abstract: We demonstrate that ustekinumab does not adversely affect semen quality or sex hormones in male patients. Ustekinumab is not detectable in semen and poses no risk to partners. Our observations support a recommendation to continue… read more here.
Keywords: dna integrity; integrity patients; sperm dna; inflammatory bowel ... See more keywords
Supplementation of quercetin for advanced DNA integrity in bull semen cryopreservation
Sign Up to like & getrecommendations! Published in 2018 at "Andrologia"
DOI: 10.1111/and.12975
Abstract: The aim of this study was to identify the effects of adding quercetin (Q) to Tris extender in order to identify levels of oxidative stress in bull sperm after freeze thawing. Ejaculates were collected via… read more here.
Keywords: bull; supplementation; tris extender; integrity ... See more keywords
How defective spermatogenesis affects sperm DNA integrity
Sign Up to like & getrecommendations! Published in 2020 at "Andrologia"
DOI: 10.1111/and.13615
Abstract: Spermatogenesis is the essential process to maintain and promote male fertility. It is extraordinarily complex with many regulatory elements and numerous steps. The process involves several cell types, regulatory molecules, repair mechanisms and epigenetic regulators.… read more here.
Keywords: spermatogenesis; sperm dna; defective spermatogenesis; spermatogenesis affects ... See more keywords
The role of sperm DNA integrity in couples with recurrent implantation failure following IVF treatment
Sign Up to like & getrecommendations! Published in 2022 at "Andrologia"
DOI: 10.1111/and.14496
Abstract: There is increasing evidence from the literature that indicates the association between impaired sperm DNA integrity and male infertility. However, the data is insufficient regarding recurrent implantation failure (RIF) and sperm DNA damage. This study… read more here.
Keywords: sperm dna; dna integrity; recurrent implantation; following ivf ... See more keywords
Impact of DNA integrity on the success rate of tissue‐based next‐generation sequencing: Lessons from nationwide cancer genome screening project SCRUM‐Japan GI‐SCREEN
Sign Up to like & getrecommendations! Published in 2020 at "Pathology International"
DOI: 10.1111/pin.13029
Abstract: In the nationwide cancer genome screening project SCRUM‐Japan GI‐SCREEN, 2590 archival formalin‐fixed paraffin‐embedded (FFPE) tumor tissues from 19 institutions were analyzed with two tissue‐based next‐generation sequencing (NGS) panels at the Clinical Laboratory Improvement Amendments (CLIA)‐certified… read more here.
Keywords: success; dna integrity; nationwide cancer; pathology ... See more keywords