DNA Logic Circuits for Cancer Theranostics.
Sign Up to like & getrecommendations! Published in 2022 at "Small"
DOI: 10.1002/smll.202108008
Abstract: Cancer diagnosis and therapeutics (theranostics) based on the tumor microenvironment (TME) and biomarkers has been an emerging approach for precision medicine. DNA nanotechnology dynamically controls the self-assembly of DNA molecules at the nanometer scale to… read more here.
Keywords: signal amplification; dna logic; logic circuits; cancer ... See more keywords
DNA Logic Nanodevices for the Sequential Imaging of Cancer Markers through Localized Catalytic Hairpin Assembly Reaction.
Sign Up to like & getrecommendations! Published in 2022 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.1c05327
Abstract: Monitoring tumor biomarkers is crucial for cancer diagnosis, progression monitoring, and treatment. However, identifying single or multiple biomarkers with the same spatial locations can cause false-positive feedback. Herein, we integrated the DNA tetrahedron (DT) structures… read more here.
Keywords: cancer; hairpin; logic nanodevices; dna logic ... See more keywords
Fluorescence-Enhanced Dual-Driven "OR-AND" DNA Logic Platform for Accurate Cell Subtype Identification.
Sign Up to like & getrecommendations! Published in 2023 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.2c05680
Abstract: Developing an endogenous stimuli-responsive and ultrasensitive DNA sensing platform that contains a logic gate biocomputation for precise cell subtype identification holds great potential for disease diagnosis and prognostic estimation. Herein, a fluorescence-enhanced "OR-AND" DNA logic… read more here.
Keywords: cell; platform; dna logic; subtype identification ... See more keywords
Fast and compact DNA logic circuits based on single-stranded gates using strand-displacing polymerase
Sign Up to like & getrecommendations! Published in 2019 at "Nature Nanotechnology"
DOI: 10.1038/s41565-019-0544-5
Abstract: DNA is a reliable biomolecule with which to build molecular computation systems. In particular, DNA logic circuits (diffusion-based) have shown good performance regarding scalability and correctness of computation. However, previous architectures of DNA logic circuits… read more here.
Keywords: single stranded; dna; logic circuits; strand displacing ... See more keywords
Developing a DNA logic gate nanosensing platform for the detection of acetamiprid
Sign Up to like & getrecommendations! Published in 2022 at "RSC Advances"
DOI: 10.1039/d2ra04794b
Abstract: This paper reports a novel fluorescence and colorimetric dual-signal-output DNA aptamer based sensor for the detection of acetamiprid residue. Acetamiprid is a new systemic broad-spectrum insecticide with high insecticidal efficiency that is widely used worldwide,… read more here.
Keywords: developing dna; dna logic; signal output; detection acetamiprid ... See more keywords
Allosteric DNAzyme-based DNA logic circuit: operations and dynamic analysis
Sign Up to like & getrecommendations! Published in 2019 at "Nucleic Acids Research"
DOI: 10.1093/nar/gky1245
Abstract: Abstract Recently, due to the dual roles of DNA and enzyme, DNAzyme has been widely used in the field of DNA circuit, which has a wide range of applications in bio-engineered system, information processing and… read more here.
Keywords: dnazyme; dna; dna logic; allosteric dnazyme ... See more keywords