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Published in 2024 at "ChemBioChem"
DOI: 10.1002/cbic.202400080
Abstract: Due to nucleic acid's programmability, it is possible to realize DNA structures with computing functions, and thus a new generation of molecular computers is evolving to solve biological and medical problems. Pioneered by Milan Stojanovic,…
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Keywords:
circuit;
dna logic;
logic gates;
dna substrates ... See more keywords
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Published in 2022 at "Small"
DOI: 10.1002/smll.202108008
Abstract: Cancer diagnosis and therapeutics (theranostics) based on the tumor microenvironment (TME) and biomarkers has been an emerging approach for precision medicine. DNA nanotechnology dynamically controls the self-assembly of DNA molecules at the nanometer scale to…
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Keywords:
signal amplification;
dna logic;
logic circuits;
cancer ... See more keywords
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Published in 2022 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.1c05327
Abstract: Monitoring tumor biomarkers is crucial for cancer diagnosis, progression monitoring, and treatment. However, identifying single or multiple biomarkers with the same spatial locations can cause false-positive feedback. Herein, we integrated the DNA tetrahedron (DT) structures…
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Keywords:
cancer;
hairpin;
logic nanodevices;
dna logic ... See more keywords
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Published in 2023 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.2c05680
Abstract: Developing an endogenous stimuli-responsive and ultrasensitive DNA sensing platform that contains a logic gate biocomputation for precise cell subtype identification holds great potential for disease diagnosis and prognostic estimation. Herein, a fluorescence-enhanced "OR-AND" DNA logic…
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Keywords:
cell;
platform;
dna logic;
subtype identification ... See more keywords
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Published in 2019 at "Nature Nanotechnology"
DOI: 10.1038/s41565-019-0544-5
Abstract: DNA is a reliable biomolecule with which to build molecular computation systems. In particular, DNA logic circuits (diffusion-based) have shown good performance regarding scalability and correctness of computation. However, previous architectures of DNA logic circuits…
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Keywords:
single stranded;
dna;
logic circuits;
strand displacing ... See more keywords
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Published in 2022 at "RSC Advances"
DOI: 10.1039/d2ra04794b
Abstract: This paper reports a novel fluorescence and colorimetric dual-signal-output DNA aptamer based sensor for the detection of acetamiprid residue. Acetamiprid is a new systemic broad-spectrum insecticide with high insecticidal efficiency that is widely used worldwide,…
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Keywords:
developing dna;
dna logic;
signal output;
detection acetamiprid ... See more keywords
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Published in 2019 at "Nucleic Acids Research"
DOI: 10.1093/nar/gky1245
Abstract: Abstract Recently, due to the dual roles of DNA and enzyme, DNAzyme has been widely used in the field of DNA circuit, which has a wide range of applications in bio-engineered system, information processing and…
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Keywords:
dnazyme;
dna;
dna logic;
allosteric dnazyme ... See more keywords
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Published in 2024 at "Nanomaterials"
DOI: 10.3390/nano14141185
Abstract: The use of DNA structures in creating multimodal logic gates bears high potential for building molecular devices and computation systems. However, due to the complex designs or complicated working principles, the implementation of DNA logic…
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Keywords:
four way;
dna logic;
logic gates;
fluorescence ... See more keywords