DNA looping by protamine follows a nonuniform spatial distribution.
Sign Up to like & getrecommendations! Published in 2021 at "Biophysical journal"
DOI: 10.1016/j.bpj.2021.04.022
Abstract: DNA looping plays an important role in cells in both regulating and protecting the genome. Often, studies of looping focus on looping by prokaryotic transcription factors like lac repressor or by structural maintenance of chromosomes… read more here.
Keywords: protamine; dna; looping protamine; spatial distribution ... See more keywords
Programmable DNA looping using engineered bivalent dCas9 complexes
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DOI: 10.1038/s41467-017-01873-x
Abstract: DNA looping is a ubiquitous and critical feature of gene regulation. Although DNA looping can be efficiently detected, tools to readily manipulate DNA looping are limited. Here we develop CRISPR-based DNA looping reagents for creation… read more here.
Keywords: bivalent dcas9; programmable dna; dna; dcas9 complexes ... See more keywords
Robustness of DNA looping across multiple cell divisions in individual bacteria
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2200061119
Abstract: Significance It is well established that certain intracellular regulators can stabilize DNA loops to greatly enhance activation or repression of gene transcription. In vitro and in vivo ensemble measurements have determined that only a few… read more here.
Keywords: looping across; dna; dna looping; multiple cell ... See more keywords