Positive and Negative Control of Enhancer-Promoter Interactions by Other DNA Loops Generates Specificity and Tunability.
Sign Up to like & getrecommendations! Published in 2019 at "Cell reports"
DOI: 10.1016/j.celrep.2019.02.002
Abstract: Enhancers are ubiquitous and critical gene-regulatory elements. However, quantitative understanding of the role of DNA looping in the regulation of enhancer action and specificity is limited. We used the Escherichia coli NtrC enhancer-σ54 promoter system… read more here.
Keywords: positive negative; enhancer promoter; control; promoter ... See more keywords
Human cohesin compacts DNA by loop extrusion
Sign Up to like & getrecommendations! Published in 2019 at "Science"
DOI: 10.1126/science.aaz4475
Abstract: Cohesin extrudes DNA loops DNA is folded into loops in eukaryotic cells by a process that depends on a ring-shaped adenosine triphosphatase complex called cohesin. Davidson et al. and Kim et al. now show that… read more here.
Keywords: cohesin; human cohesin; loop extrusion; extrudes dna ... See more keywords