DNA melting and energetics of the double helix.
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DOI: 10.1016/j.plrev.2017.11.012
Abstract: Studying melting and energetics of the DNA double helix has been one of the major topics of molecular biophysics over the past six decades. The main objective of this article is to overview the current… read more here.
Keywords: double helix; dna; model; dna melting ... See more keywords
Statistical mechanics of a double-stranded rod model for DNA melting and elasticity.
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DOI: 10.1039/d0sm00521e
Abstract: The double-helical topology of DNA molecules observed at room temperature in the absence of any external loads can be disrupted by increasing the bath temperature or by applying tensile forces, leading to spontaneous strand separation… read more here.
Keywords: temperature; statistical mechanics; double stranded; dna melting ... See more keywords
TaqMan probes as blocking agents for enriched PCR amplification and DNA melting analysis of mutant genes.
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DOI: 10.2144/000114515
Abstract: Asymmetric PCR and DNA melting analysis with TaqMan probes applied for mutation detection is effectively used in clinical diagnostics. The method is simple, cost-effective, and carried out in a closed-tube format, minimizing time, labor, and… read more here.
Keywords: dna melting; blocking agents; taqman probes; melting analysis ... See more keywords