The epigenetic roles of DNA N6-Methyladenine (6 mA) modification in eukaryotes.
Sign Up to like & getrecommendations! Published in 2020 at "Cancer letters"
DOI: 10.1016/j.canlet.2020.08.025
Abstract: The DNA N6-methyladenine (6 mA) modification is a prevalent epigenetic mark in prokaryotes, but the low abundance of 6 mA in eukaryotes has recently received attention. The possible role of 6 mA as an epigenetic mark in eukaryotes… read more here.
Keywords: epigenetic roles; roles dna; modification eukaryotes; methyladenine modification ... See more keywords
GC6mA-Pred: A deep learning approach to identify DNA N6-methyladenine sites in the rice genome.
Sign Up to like & getrecommendations! Published in 2022 at "Methods"
DOI: 10.1016/j.ymeth.2022.02.001
Abstract: MOTIVATION DNA N6-methyladenine (6mA) is a pivotal DNA modification for various biological processes. More accurate prediction of 6mA methylation sites plays an irreplaceable part in grasping the internal rationale of related biological activities. However, the… read more here.
Keywords: gc6ma pred; sequence; information; dna methyladenine ... See more keywords
A review of methods for predicting DNA N6-methyladenine sites
Sign Up to like & getrecommendations! Published in 2022 at "Briefings in bioinformatics"
DOI: 10.1093/bib/bbac514
Abstract: Deoxyribonucleic acid(DNA) N6-methyladenine plays a vital role in various biological processes, and the accurate identification of its site can provide a more comprehensive understanding of its biological effects. There are several methods for 6mA site… read more here.
Keywords: review methods; dna methyladenine; methods predicting; computer methods ... See more keywords
i6mA-Pred: identifying DNA N6-methyladenine sites in the rice genome
Sign Up to like & getrecommendations! Published in 2019 at "Bioinformatics"
DOI: 10.1093/bioinformatics/btz015
Abstract: Motivation DNA N6-methyladenine (6mA) is associated with a wide range of biological processes. Since the distribution of 6mA site in the genome is non-random, accurate identification of 6mA sites is crucial for understanding its biological… read more here.
Keywords: dna; sites rice; rice genome; i6ma pred ... See more keywords
Molecular characterization of Plasmodium falciparum DNA-3-methyladenine glycosylase
Sign Up to like & getrecommendations! Published in 2020 at "Malaria Journal"
DOI: 10.1186/s12936-020-03355-w
Abstract: The emergence of artemisinin-resistant malaria parasites highlights the need for novel drugs and their targets. Alkylation of purine bases can hinder DNA replication and if unresolved would eventually result in cell death. DNA-3-methyladenine glycosylase (MAG)… read more here.
Keywords: dna; pfmag; methyladenine glycosylase; activity ... See more keywords
DNA N6-Methyladenine Modification in Wild and Cultivated Soybeans Reveals Different Patterns in Nucleus and Cytoplasm
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2020.00736
Abstract: DNA 6mA modification, an important newly discovered epigenetic mark, plays a crucial role in organisms and has been attracting more and more attention in recent years. The soybean is economically the most important bean in… read more here.
Keywords: cultivated soybeans; 6ma modification; methyladenine modification; modification ... See more keywords
i6mA-DNCP: Computational Identification of DNA N6-Methyladenine Sites in the Rice Genome Using Optimized Dinucleotide-Based Features
Sign Up to like & getrecommendations! Published in 2019 at "Genes"
DOI: 10.3390/genes10100828
Abstract: DNA N6-methyladenine (6mA) plays an important role in regulating the gene expression of eukaryotes. Accurate identification of 6mA sites may assist in understanding genomic 6mA distributions and biological functions. Various experimental methods have been applied… read more here.
Keywords: i6ma dncp; dna; sites rice; 6ma sites ... See more keywords
DNA N6-Methyladenine Modification in Plant Genomes—A Glimpse into Emerging Epigenetic Code
Sign Up to like & getrecommendations! Published in 2020 at "Plants"
DOI: 10.3390/plants9020247
Abstract: N6-methyladenine (6mA) is a DNA base modification at the 6th nitrogen position; recently, it has been resurfaced as a potential reversible epigenetic mark in eukaryotes. Despite its existence, 6mA was considered to be absent due… read more here.
Keywords: plant; plant genomes; modification plant; methyladenine modification ... See more keywords
6mA-Pred: identifying DNA N6-methyladenine sites based on deep learning
Sign Up to like & getrecommendations! Published in 2021 at "PeerJ"
DOI: 10.7717/peerj.10813
Abstract: With the accumulation of data on 6mA modification sites, an increasing number of scholars have begun to focus on the identification of 6mA sites. Despite the recognized importance of 6mA sites, methods for their identification… read more here.
Keywords: pred identifying; 6ma pred; identifying dna; 6ma sites ... See more keywords