Association of Race and Poverty Status With DNA Methylation–Based Age
Sign Up to like & getrecommendations! Published in 2023 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2023.6340
Abstract: Key Points Question As a biomarker of biological aging, does DNA methylation (DNAm) adequately assess the rate of change in aging over time among socioeconomically diverse middle-aged African American and White adults? Findings In this… read more here.
Keywords: race; african american; dna methylation; poverty ... See more keywords
Individual and joint performance of DNA methylation profiles, genetic risk score and environmental risk scores for predicting breast cancer risk
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Oncology"
DOI: 10.1002/1878-0261.12594
Abstract: DNA methylation patterns in the blood, genetic risk scores (GRSs), and environmental risk factors can potentially improve breast cancer (BC) risk prediction. We assessed the individual and joint predictive performance of methylation, GRS, and environmental… read more here.
Keywords: methylation; risk; environmental risk; performance ... See more keywords
The DNA methylation landscape of hematological malignancies: an update
Sign Up to like & getrecommendations! Published in 2020 at "Molecular Oncology"
DOI: 10.1002/1878-0261.12744
Abstract: The rapid advances in high‐throughput sequencing technologies have made it more evident that epigenetic modifications orchestrate a plethora of complex biological processes. During the last decade, we have gained significant knowledge about a wide range… read more here.
Keywords: methylation; landscape hematological; methylation landscape; hematological malignancies ... See more keywords
Identification and validation of novel DNA methylation markers for early diagnosis of lung adenocarcinoma
Sign Up to like & getrecommendations! Published in 2020 at "Molecular Oncology"
DOI: 10.1002/1878-0261.12767
Abstract: Lung cancer has the highest mortality of all cancers worldwide. Epigenetic alterations have emerged as potential biomarkers for early diagnosis of various cancer tissue types. To identify methylation markers for early diagnosis of lung adenocarcinoma,… read more here.
Keywords: lung adenocarcinoma; methylation; dna methylation; methylation markers ... See more keywords
Epigenetic–smoking interaction reveals histologically heterogeneous effects of TRIM27 DNA methylation on overall survival among early‐stage NSCLC patients
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DOI: 10.1002/1878-0261.12785
Abstract: Tripartite motif containing 27 (TRIM27) is highly expressed in lung cancer, including non‐small‐cell lung cancer (NSCLC). Here, we profiled DNA methylation of lung adenocarcinoma (LUAD) and lung squamous cell carcinoma (LUSC) tumours from 613 early‐stage… read more here.
Keywords: methylation; nsclc patients; early stage; overall survival ... See more keywords
Computational characterization of domain-segregated 3D chromatin structure and segmented DNA methylation status in carcinogenesis.
Sign Up to like & getrecommendations! Published in 2021 at "Molecular oncology"
DOI: 10.1002/1878-0261.13127
Abstract: The high-order chromatin structure, together with DNA methylation and other epigenetic marks, plays a vital role in gene regulation and displays abnormal status in cancer cells. Theoretical analyses are expected to provide a more unified… read more here.
Keywords: carcinogenesis; chromatin structure; dna methylation;
Genes regulated by DNA methylation are involved in distinct phenotypes during melanoma progression and are prognostic factors for patients
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Oncology"
DOI: 10.1002/1878-0261.13185
Abstract: In addition to mutations, epigenetic alterations are important contributors to malignant transformation and tumor progression. The aim of this work was to identify epigenetic events in which promoter or gene body DNA methylation induces gene… read more here.
Keywords: melanoma progression; progression; dna methylation; gene expression ... See more keywords
Epigenome-wide DNA methylation analysis of myasthenia gravis.
Sign Up to like & getrecommendations! Published in 2023 at "FEBS open bio"
DOI: 10.1002/2211-5463.13656
Abstract: Myasthenia gravis (MG) is a common neuromuscular junction (NMJ) disorder and autoimmune disease mediated by several antibodies. Several studies have shown that genetic factors play an important role in MG pathogenesis. To gain insight into… read more here.
Keywords: methylation; methylation analysis; dna methylation; wide dna ... See more keywords
Implication for DNA methylation involved in the host transfer of diamondback moth, Plutella xylostella (L.).
Sign Up to like & getrecommendations! Published in 2019 at "Archives of insect biochemistry and physiology"
DOI: 10.1002/arch.21600
Abstract: DNA methylation exerts extensive impacts on gene expression of various living organisms exposed to environmental variation. However, little is known whether DNA methylation is involved in the host transfer of diamondback moth, Plutella xylostella (L.),… read more here.
Keywords: xylostella; methylation; dna methylation; host transfer ... See more keywords
Comparison of DNA methylation patterns across tissue types in infants with tetralogy of Fallot
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DOI: 10.1002/bdr2.2090
Abstract: Environmental factors may influence the development of tetralogy of Fallot (TOF), and DNA methylation patterns may reveal specific chemical signatures of perturbations during cardiac development. We investigated whether blood and buccal cells could be viable… read more here.
Keywords: dna methylation; tetralogy fallot; methylation patterns;
DNA methylation profile of lip tissue from congenital nonsyndromic cleft lip and palate patients by whole‐genome bisulfite sequencing
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DOI: 10.1002/bdr2.2102
Abstract: Congenital nonsyndromic cleft lip and palate (NSCLP) is one of the most common malformations worldwide. DNA methylation has been implicated in many diseases. However, its involvement in lip tissue from NSCLP is not well understood.… read more here.
Keywords: methylation; dna methylation; lip tissue; congenital nonsyndromic ... See more keywords