DNA recognition by linear indole-biphenyl DNA minor groove ligands.
Sign Up to like & getrecommendations! Published in 2019 at "Biophysical chemistry"
DOI: 10.1016/j.bpc.2018.11.004
Abstract: Linear heterocyclic cations are interesting DNA minor groove ligands due to their lack of isohelical curvature classically associated with groove-binding compounds. We determined the DNA binding properties of four related dications harboring a linear indole-biphenyl… read more here.
Keywords: dna minor; dna; indole biphenyl; groove ... See more keywords
Synthesis and Evaluation of Novel DNA Minor Groove Binders as Antiamoebic Agents
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DOI: 10.3390/antibiotics11070935
Abstract: The free-living amoeba Acanthamoeba castellanii is responsible for the central nervous infection granulomatous amoebic encephalitis and sight-threatening infection Acanthamoeba keratitis. Moreover, no effective treatment is currently present, and a combination drug therapy is used. In… read more here.
Keywords: compounds mgb3; minor groove; groove binders; dna minor ... See more keywords