Optimizing on-chip concentration of DNA molecules against a nanoslit barrier
Sign Up to like & getrecommendations! Published in 2020 at "Microfluidics and Nanofluidics"
DOI: 10.1007/s10404-020-02392-w
Abstract: On-chip concentration method for deoxyribonucleic acid (DNA) molecules is preconcentrating DNA molecules before analyses using nanometer-sized structures formed in a microchannel and is effective in improving the sensitivity in DNA analyses using microfluidic devices. Although… read more here.
Keywords: dna molecules; dna; concentration dna; chip concentration ... See more keywords
Design of customizable long linear DNA substrates with controlled end modifications for single-molecule studies.
Sign Up to like & getrecommendations! Published in 2019 at "Analytical biochemistry"
DOI: 10.1016/j.ab.2019.113541
Abstract: Many strategies have been developed to manipulate DNA molecules and investigate protein-DNA interactions with single-molecule resolution. Often, these require long DNA molecules with a length of several 10s of kb that are chemically modified at… read more here.
Keywords: dna molecules; single molecule; dna; dna substrates ... See more keywords
An efficient method to quantitatively detect competitive adsorption of DNA on single-walled carbon nanotube surfaces.
Sign Up to like & getrecommendations! Published in 2020 at "Analytical biochemistry"
DOI: 10.1016/j.ab.2020.113776
Abstract: In this study, we quantitatively detected adsorption and desorption of DNA molecules that competed with sodium cholate (SC) molecules on single-walled carbon nanotubes (SWNTs) by fluorescence spectroscopy. In previous studies, competitive adsorption and/or replacement were… read more here.
Keywords: adsorption; dna molecules; dna; competitive adsorption ... See more keywords
Detection and Separation of DNA and Silver Nanoparticles Using a Solid-State Nanopore
Sign Up to like & getrecommendations! Published in 2023 at "ACS Omega"
DOI: 10.1021/acsomega.3c00152
Abstract: Nanopore sensors, a new generation of single-molecule sensors, are increasingly used to detect and analyze various analytes and have great potential for rapid gene sequencing. However, there are still some problems in the preparation of… read more here.
Keywords: dna; silver nanoparticles; detection; nanopore sensors ... See more keywords
Graph Computation Using Algorithmic Self-Assembly of DNA Molecules.
Sign Up to like & getrecommendations! Published in 2022 at "ACS synthetic biology"
DOI: 10.1021/acssynbio.2c00120
Abstract: DNA molecules have been used as novel computing tools, by which Synthetic DNA was designed to execute computing processes with a programmable sequence. Here, we proposed a parallel computing method using DNA origamis as agents… read more here.
Keywords: dna; computation using; using algorithmic; graph computation ... See more keywords
ReaxFF-based molecular dynamics simulation of DNA molecules destruction in cancer cells by plasma ROS
Sign Up to like & getrecommendations! Published in 2019 at "Physics of Plasmas"
DOI: 10.1063/1.5097243
Abstract: Medical applications of plasma have been a hot topic of research recently. Studies have shown that cold atmospheric pressure plasma (CAP) plays a beneficial role in cancer treatments and can selectively kill cancer cells. Some… read more here.
Keywords: dna molecules; cancer cells; simulation; damage ... See more keywords
Detection of rare mutations, copy number alterations, and methylation in the same template DNA molecules.
Sign Up to like & getrecommendations! Published in 2023 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2220704120
Abstract: The analysis of cell-free DNA (cfDNA) from plasma offers great promise for the earlier detection of cancer. At present, changes in DNA sequence, methylation, or copy number are the most sensitive ways to detect the… read more here.
Keywords: methylation; dna; template; copy number ... See more keywords
Approaches for introducing large DNA molecules into bacterial cells.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of applied microbiology"
DOI: 10.1093/jambio/lxad059
Abstract: Engineering of the bacterial genome plays a key role in systems biology and synthetic biology. Genetic engineering of the bacterial genome involves the design and synthesis of large DNA molecules. However, functional studies of the… read more here.
Keywords: molecules bacterial; large dna; dna molecules; biology ... See more keywords
How does temperature impact the conformation of single DNA molecules below melting temperature?
Sign Up to like & getrecommendations! Published in 2018 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkx1285
Abstract: Abstract The double stranded DNA molecule undergoes drastic structural changes during biological processes such as transcription during which it opens locally under the action of RNA polymerases. Local spontaneous denaturation could contribute to this mechanism… read more here.
Keywords: dna molecules; melting temperature; temperature; dna ... See more keywords
Helical liquid in carbon nanotubes wrapped with DNA molecules
Sign Up to like & getrecommendations! Published in 2018 at "Physical Review B"
DOI: 10.1103/physrevb.98.195405
Abstract: The measured electric resistance of carbon nanotubes wrapped with DNA molecules depends strongly on the spin of the injected electrons. Motivated by these experiments, we study the effect of helix-shaped potentials on the electronic spectrum… read more here.
Keywords: dna molecules; carbon; nanotubes wrapped; carbon nanotubes ... See more keywords
DNA sequence–directed shape change of photopatterned hydrogels via high-degree swelling
Sign Up to like & getrecommendations! Published in 2017 at "Science"
DOI: 10.1126/science.aan3925
Abstract: DNA molecules direct the swelling of cross-linked hydrogels with shape changes in response to different biomolecular signals. Getting a hold with DNA Stimuli-responsive materials can respond to physical or chemical cues to trigger changes in… read more here.
Keywords: dna molecules; shape; dna; shape changes ... See more keywords