Articles with "dna morphology" as a keyword



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DNA Morphology: Global Alteration of DNA Topological States Induced by Chemotherapeutic Agents and Its Implication in Cancer

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Published in 2023 at "ChemBioChem"

DOI: 10.1002/cbic.202200715

Abstract: The dynamic topological states of chromosomal DNA regulate many cellular fundamental processes universally in all three domains of life, that is, bacteria, archaea, and eukaryotes. DNA‐binding proteins maintain the regional and global supercoiling of the… read more here.

Keywords: dna morphology; dna; dna binding; chemotherapeutic agents ... See more keywords
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Effect of testosterone and its aliphatic and aromatic dimers on DNA morphology.

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Published in 2017 at "International journal of biological macromolecules"

DOI: 10.1016/j.ijbiomac.2016.09.090

Abstract: Conjugation of DNA with testosterone and it aliphatic dimer (alip) and aromatic dimer (arom) was investigated in aqueous solution at pH 7.4. Multiple spectroscopic methods, transmission electron microscopy (TEM) and molecular modeling were used to… read more here.

Keywords: microscopy; dna; dimer; testosterone ... See more keywords