Supramolecular Modulator Assisted Cryo‐Engineered Porous Cu‐DNA Nano‐Vehicles for Versatile Theranostic Agent Delivery
Sign Up to like & getrecommendations! Published in 2024 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202401885
Abstract: DNA nanotechnology combines structural design with therapeutic functions via programmable DNA motifs, but faces challenges in drug loading capacity. Herein a pore‐engineering strategy is reported to develop a highly porous, universal DNA nano‐vehicle through coordination… read more here.
Keywords: dna nano; chemistry; cryo engineered; dna ... See more keywords
Gold-Nanoparticle-Mediated Assembly of High-Order DNA Nano-Architectures.
Sign Up to like & getrecommendations! Published in 2022 at "Small"
DOI: 10.1002/smll.202200824
Abstract: Constructing high-order DNA nano-architectures in large sizes is of critical significance for the application of DNA nanotechnology. Robust and flexible design strategies together with easy protocols to construct high-order large-size DNA nano-architectures remain highly desirable.… read more here.
Keywords: dna nano; dna; nano architectures; high order ... See more keywords
Rolling Circle Amplification-Based DNA Nano-Assembly for Targeted Drug Delivery and Gene Therapy.
Sign Up to like & getrecommendations! Published in 2022 at "Biomacromolecules"
DOI: 10.1021/acs.biomac.2c01271
Abstract: Combining the killing ability of chemotherapy drugs on tumor cells with the inhibiting ability of genetic drugs on tumor cell growth, a dual drug delivery system loaded with therapy drugs and siRNA has gradually received… read more here.
Keywords: nano assembly; rolling circle; drug delivery; dna nano ... See more keywords
Near-infrared-traceable DNA nano-hydrolase: specific eradication of telomeric G-overhang in vivo
Sign Up to like & getrecommendations! Published in 2020 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkaa693
Abstract: Abstract Telomeric DNA, whose length homeostasis is closely correlated with immortality of cancer cells, is regarded as a molecular clock for cellular lifespan. Regarding the capacity in forming G-quadruplex, G-rich 3′-overhang (G-overhang) has been considered… read more here.
Keywords: nano hydrolase; overhang; telomeric overhang; dna nano ... See more keywords