Design of supramolecular hybrid nanomaterials comprising peptide-based supramolecular nanofibers and in situ generated DNA nanoflowers through rolling circle amplification.
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DOI: 10.1039/d2nr04556g
Abstract: The artificial construction of multicomponent supramolecular materials comprising plural supramolecular architectures that are assembled orthogonally from their constituent molecules has attracted growing attention. Here, we describe the design and development of multicomponent supramolecular materials by… read more here.
Keywords: peptide based; rolling circle; circle amplification; dna nanoflowers ... See more keywords
DNA Nanoflowers’ Amelioration of Lupus Symptoms in Mice via Blockade of TLR7/9’s Signal
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DOI: 10.3390/ijms232416030
Abstract: Inhibitory oligodeoxynucleotides (INH-ODN) can exert an immunomodulatory effect to specifically block TLR7 and TLR9 signaling in systemic lupus erythematosus (SLE). To extend the half-life of INH-ODN in vivo, the phosphorothioate backbone, instead of the native… read more here.
Keywords: dna nanoflowers; inh odn; lupus; tlr7 tlr9 ... See more keywords