DNA Nanostructure-Templated Multivalency Enables Broad-Spectrum Virus Inhibition.
Sign Up to like & getrecommendations! Published in 2025 at "Advanced science"
DOI: 10.1002/advs.202513710
Abstract: The rapid evolution and antigenic diversity of influenza A viruses (IAVs) continue to challenge antiviral strategies, highlighting the need for broadly effective and modular therapeutic platforms. While single-domain nanobodies and DNA aptamer-based inhibitors have emerged… read more here.
Keywords: broad spectrum; inhibition; dna nanostructure; geometry ... See more keywords
DNA nanostructure-directed assembly of metal nanoparticle superlattices
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Nanoparticle Research"
DOI: 10.1007/s11051-018-4225-3
Abstract: Structural DNA nanotechnology provides unique, well-controlled, versatile, and highly addressable motifs and templates for assembling materials at the nanoscale. These methods to build from the bottom-up using DNA as a construction material are based on… read more here.
Keywords: assembly metal; dna; nanostructure directed; directed assembly ... See more keywords
Design of a cost-effective inverted tetrahedral DNA nanostructure – Based interfacial probe for electrochemical biosensing with enhanced performance
Sign Up to like & getrecommendations! Published in 2021 at "Microchemical Journal"
DOI: 10.1016/j.microc.2021.106455
Abstract: Abstract DNA nanostructure-based interfacial probes have been an emerging candidate for constructing next-generation biosensors. However, one major limitation of these sensors is the high cost for preparing DNA nanostructure probes caused by the requirement of… read more here.
Keywords: dna nanostructure; dna; probe; cost ... See more keywords
Ratiometric Fluorescent DNA Nanostructure for Mitochondrial ATP Imaging in Living Cells Based on Hybridization Chain Reaction.
Sign Up to like & getrecommendations! Published in 2021 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.1c00176
Abstract: For intracellular molecular detection, the appropriate probes should include the abilities to enter target cells noninvasively, target specific sites, and then respond to the analytes reliably. Herein, a ratiometric fluorescent DNA nanostructure (RFDN) was designed… read more here.
Keywords: cy3; living cells; atp; dna nanostructure ... See more keywords
Net-Shaped DNA Nanostructure-Based Lateral Flow Assays for Rapid and Sensitive SARS-CoV-2 Detection.
Sign Up to like & getrecommendations! Published in 2024 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.3c03698
Abstract: Lateral flow assay (LFA)-based rapid antigen tests are experiencing extensive global uptake as an expeditious and highly effective modality for the screening of viral infections during the COVID-19 pandemic. While these devices have played a… read more here.
Keywords: sars cov; detection; lateral flow; dna nanostructure ... See more keywords
A Novel Immunoprobe Strategy Integrating Tetrahedral DNA Nanostructure and Protein A for Sensitivity Enhancement: Application in Lead Ion Detection.
Sign Up to like & getrecommendations! Published in 2025 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.5c02529
Abstract: Immunochromatographic assay (ICA) has been extensively utilized for on-site detection to ensure food safety. However, maintaining the bioactivity of immunoprobes while achieving efficient antibody labeling remains a significant challenge. In this study, a novel immunoprobe… read more here.
Keywords: detection; tetrahedral dna; dna nanostructure; novel immunoprobe ... See more keywords
DNA nanotechnology in the undergraduate laboratory: Electrophoretic analysis of DNA nanostructure biostability.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of chemical education"
DOI: 10.1021/acs.jchemed.2c00656
Abstract: The field of DNA nanotechnology has grown rapidly in the last decade and has expanded to multiple laboratories. While lectures in DNA nanotechnology have been introduced in some institutions, laboratory components at the undergraduate level… read more here.
Keywords: dna; nanotechnology; biostability; dna nanostructure ... See more keywords
A Targeted Octahedral DNA Nanostructure Co-delivers siME3 and Doxorubicin to Enhance Collateral Lethality in ME2-Deficient Pancreatic Cancer.
Sign Up to like & getrecommendations! Published in 2024 at "Nano letters"
DOI: 10.1021/acs.nanolett.4c05123
Abstract: The genetic characteristics of pancreatic cancer (PC) are being revealed, but treatment strategies based on these profiles are developing slowly. About one-third of PC patients harbor SMAD4 mutations, with its homozygous deletions often accompanied by… read more here.
Keywords: me2 deficient; nanostructure; sime3 doxorubicin; dna nanostructure ... See more keywords
Geometry of a DNA Nanostructure Influences Its Endocytosis: Cellular Study on 2D, 3D, and in Vivo Systems.
Sign Up to like & getrecommendations! Published in 2022 at "ACS nano"
DOI: 10.1021/acsnano.2c01382
Abstract: Fabrication of nanoscale DNA devices to generate 3D nano-objects with precise control of shape, size, and presentation of ligands has shown tremendous potential for therapeutic applications. The interactions between the cell membrane and different topologies… read more here.
Keywords: dna; dna nanostructure; geometry; geometry dna ... See more keywords
Design of DNA nanostructure-based interfacial probes for the electrochemical detection of nucleic acids directly in whole blood† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c7sc04663d
Sign Up to like & getrecommendations! Published in 2018 at "Chemical Science"
DOI: 10.1039/c7sc04663d
Abstract: A novel DNA nanostructure-based electrochemical (E-nanoDNA) sensor is proposed for one-step reagentless detection of biomolecules in flowing samples. read more here.
Keywords: nanostructure based; detection; design dna; dna nanostructure ... See more keywords
DNA nanostructure-based fluorescent probes for cellular sensing
Sign Up to like & getrecommendations! Published in 2020 at "Analytical Methods"
DOI: 10.1039/d0ay00105h
Abstract: Monitoring the distribution and concentration fluctuation of cellular compositions at the molecular level is of great significance in biological studies and medical diagnostics. Towards this goal, lots of fluorescent probes for cellular imaging have been… read more here.
Keywords: nanostructure based; probes cellular; based fluorescent; fluorescent probes ... See more keywords