DNA Nanotechnology-Based Biosensors and Therapeutics.
Sign Up to like & getrecommendations! Published in 2021 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202002205
Abstract: Over the past few decades, DNA nanotechnology engenders a vast variety of programmable nanostructures utilizing Watson-Crick base pairing. Due to their precise engineering, unprecedented programmability, and intrinsic biocompatibility, DNA nanostructures cannot only interact with small… read more here.
Keywords: biosensors therapeutics; dna nanostructures; nanotechnology; nanotechnology based ... See more keywords
Engineering DNA Nanostructures to Manipulate Immune Receptor Signaling and Immune Cell Fates.
Sign Up to like & getrecommendations! Published in 2021 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202101844
Abstract: Immune cells sense, communicate, and logically integrate a multitude of environmental signals to make important cell-fate decisions and fulfill their effector functions. These processes are initiated and regulated by a diverse array of immune receptors… read more here.
Keywords: engineering; dna; dna nanostructures; receptor signaling ... See more keywords
Dendrimeric DNA Nanostructures as Scaffolds for Efficient Bidirectional BRET–FRET Cascades
Sign Up to like & getrecommendations! Published in 2017 at "Advanced Optical Materials"
DOI: 10.1002/adom.201700181
Abstract: DNA scaffolds offer advantages for biomolecular devices capable of generating and controlling energy flow. Through attachment of the bioluminescent protein luciferase and precise positioning of organic fluorophores, these structures form efficient self-illuminating energy transfer cascades.… read more here.
Keywords: energy transfer; dendrimeric dna; energy; dna ... See more keywords
Dynamic Transformation of DNA Nanostructures inside Living Cells.
Sign Up to like & getrecommendations! Published in 2022 at "ChemPlusChem"
DOI: 10.1002/cplu.202100519
Abstract: DNA nanostructures, that show sequence programmable responsiveness to intracellular signals, have been explored as potential candidates of artificial dynamic functional structures in living cells. Recently, we developed a series of intracellular signals responding DNA nanostructures… read more here.
Keywords: dynamic transformation; dna; living cells; dna nanostructures ... See more keywords
Engineering the Surface Properties of DNA Nanostructures by Tuning the Valency of Assembling Species for Biomedical Applications.
Sign Up to like & getrecommendations! Published in 2022 at "Macromolecular bioscience"
DOI: 10.1002/mabi.202200248
Abstract: Self-assembled DNA nanostructures hold great potentials in biomedical applications. Nevertheless, the negatively charged DNA backbone and susceptivity to enzyme degradation pose challenges to this regard. Engineering the surface properties of DNA nanostructures by assembling DNA… read more here.
Keywords: engineering surface; surface properties; dna; biomedical applications ... See more keywords
A Molecular Hero Suit for In Vitro and In Vivo DNA Nanostructures.
Sign Up to like & getrecommendations! Published in 2019 at "Small"
DOI: 10.1002/smll.201805386
Abstract: Precise control of DNA base pairing has rapidly developed into a field full of diverse nanoscale structures and devices that are capable of automation, performing molecular analyses, mimicking enzymatic cascades, biosensing, and delivering drugs. This… read more here.
Keywords: dna; hero suit; hero; dna nanostructures ... See more keywords
Ionic Current Fluctuation and Orientation of Tetrahedral DNA Nanostructures in a Solid-State Nanopore.
Sign Up to like & getrecommendations! Published in 2022 at "Small"
DOI: 10.1002/smll.202107237
Abstract: Understanding the dynamic behavior of a nanostructure translocating through a nanopore is important for various applications. In this paper, the characteristics in ion current traces of tetrahedral DNA nanostructures (TDN) translocating through a solid-state nanopore… read more here.
Keywords: state; orientation; solid state; tetrahedral dna ... See more keywords
Self-Assembly of DNA Nanostructures in Different Cations.
Sign Up to like & getrecommendations! Published in 2023 at "Small"
DOI: 10.1002/smll.202300040
Abstract: The programmable nature of DNA allows the construction of custom-designed static and dynamic nanostructures, and assembly conditions typically require high concentrations of magnesium ions that restricts their applications. In other solution conditions tested for DNA… read more here.
Keywords: dna; assembly dna; self assembly; dna nanostructures ... See more keywords
Functionalizing DNA nanostructures for therapeutic applications.
Sign Up to like & getrecommendations! Published in 2021 at "Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology"
DOI: 10.1002/wnan.1729
Abstract: Recent advances in nanotechnology have enabled rapid progress in many areas of biomedical research, including drug delivery, targeted therapies, imaging, and sensing. The emerging field of DNA nanotechnology, in which oligonucleotides are designed to self-assemble… read more here.
Keywords: functionalizing dna; biology; dna nanostructures; nanotechnology ... See more keywords
Engineering DNA quadruplexes in DNA nanostructures for biosensor construction
Sign Up to like & getrecommendations! Published in 2021 at "Nano Research"
DOI: 10.1007/s12274-021-3869-y
Abstract: DNA quadruplexes are nucleic acid conformations comprised of four strands. They are prevalent in human genomes and increasing efforts are being directed toward their engineering. Taking advantage of the programmability of Watson-Crick base-pairing and conjugation… read more here.
Keywords: dna; construction; dna quadruplexes; dna nanostructures ... See more keywords
Homogeneous biorecognition reaction-induced assembly of DNA nanostructures for ultrasensitive electrochemical detection of kanamycin antibiotic.
Sign Up to like & getrecommendations! Published in 2021 at "Analytica chimica acta"
DOI: 10.1016/j.aca.2021.338317
Abstract: By the employment of a homogeneous biorecognition reaction to induce the assembled formation of DNA nanostructures at an electrode, herein we develop a novel biosensing method for the ultrasensitive electrochemical detection of kanamycin (Kana) antibiotic.… read more here.
Keywords: detection; reaction; dna nanostructures; biorecognition reaction ... See more keywords