Initiation of homologous recombination at DNA nicks
Sign Up to like & getrecommendations! Published in 2018 at "Nucleic Acids Research"
DOI: 10.1093/nar/gky588
Abstract: Abstract Discontinuities in only a single strand of the DNA duplex occur frequently, as a result of DNA damage or as intermediates in essential nuclear processes and DNA repair. Nicks are the simplest of these… read more here.
Keywords: initiation homologous; dna; homologous recombination; strand ... See more keywords
Exo1 protects DNA nicks from ligation to promote crossover formation during meiosis
Sign Up to like & getrecommendations! Published in 2023 at "PLOS Biology"
DOI: 10.1371/journal.pbio.3002085
Abstract: In most sexually reproducing organisms crossing over between chromosome homologs during meiosis is essential to produce haploid gametes. Most crossovers that form in meiosis in budding yeast result from the biased resolution of double Holliday… read more here.
Keywords: crossover; meiosis; dna nicks; exo1 ... See more keywords