Novel enzymatic single-nucleotide modification of DNA oligomer: prevention of incessant incorporation of nucleotidyl transferase by ribonucleotide-borate complex
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DOI: 10.1093/nar/gkz612
Abstract: Abstract Terminal deoxynucleotidyl transferase (TdT), which mediates template-independent polymerization with low specificity for nucleotides, has been used for nucleotide extension of DNA oligomers. One concern is that it is difficult to control the number of… read more here.
Keywords: tdt; dna; single nucleotide; incorporation ... See more keywords