The Creation of DNA Origami-Based Supramolecular Nanostructures for Cancer Therapy.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202301066
Abstract: DNA origami technology, a unique type of DNA nanotechnology, has attracted much attention from researchers and has been applied in various fields. Through exquisite design and precise self-assembly of four kinds of deoxyribonucleotides, DNA origami… read more here.
Keywords: cancer therapy; dna; dna origami;
Rationally Designed DNA-Origami Nanomaterials for Drug Delivery In Vivo.
Sign Up to like & getrecommendations! Published in 2018 at "Advanced materials"
DOI: 10.1002/adma.201804785
Abstract: The recent decades have seen a surge of new nanomaterials designed for efficient drug delivery. DNA nanotechnology has been developed to construct sophisticated 3D nanostructures and artificial molecular devices that can be operated at the… read more here.
Keywords: drug; drug delivery; dna origami;
Inducing Lipid Domains in Membranes by Self‐Assembly of DNA Origami
Sign Up to like & getrecommendations! Published in 2023 at "Advanced Materials Interfaces"
DOI: 10.1002/admi.202202500
Abstract: Self‐assembly of biological molecules and structures is a fundamental property of life. Whereas most biological functions are based on self‐assembled proteins and protein complexes, the self‐assembly of lipids is important for the spatial organization of… read more here.
Keywords: self assembly; lipid domains; membrane; dna origami ... See more keywords
Structure‐Dependent Electrical Conductance of DNA Origami Nanowires
Sign Up to like & getrecommendations! Published in 2022 at "ChemBioChem"
DOI: 10.1002/cbic.202200454
Abstract: Exploring the structural and electrical properties of DNA origami nanowires is an important endeavor for the advancement of DNA nanotechnology and DNA nanoelectronics. Highly conductive DNA origami nanowires are a desirable target for creating low‐cost… read more here.
Keywords: electrical conductance; dna origami; origami nanowires;
Periodic Operation of a Dynamic DNA Origami Structure Utilizing the Hydrophilic-Hydrophobic Phase-Transition of Stimulus-Sensitive Polypeptides.
Sign Up to like & getrecommendations! Published in 2019 at "Small"
DOI: 10.1002/smll.201903541
Abstract: Dynamic DNA nanodevices are designed to perform structure-encoded motion actuated by a variety of different physicochemical stimuli. In this context, hybrid devices utilizing other components than DNA have the potential to considerably expand the library… read more here.
Keywords: dna origami; dynamic dna; transition; structure ... See more keywords
DNA Origami Catenanes Templated by Gold Nanoparticles.
Sign Up to like & getrecommendations! Published in 2020 at "Small"
DOI: 10.1002/smll.201905987
Abstract: Mechanically interlocked molecules have marked a breakthrough in the field of topological chemistry and boosted the vigorous development of molecular machinery. As an archetypal example of the interlocked molecules, catenanes comprise macrocycles that are threaded… read more here.
Keywords: gold nanoparticles; templated gold; origami catenanes; catenanes templated ... See more keywords
Environment-Dependent Stability and Mechanical Properties of DNA Origami Six-Helix Bundles with Different Crossover Spacings.
Sign Up to like & getrecommendations! Published in 2022 at "Small"
DOI: 10.1002/smll.202107393
Abstract: The internal design of DNA nanostructures defines how they behave in different environmental conditions, such as endonuclease-rich or low-Mg2+ solutions. Notably, the inter-helical crossovers that form the core of such DNA objects have a major… read more here.
Keywords: dna; dependent stability; mechanical properties; dna origami ... See more keywords
Nanoscale Organization of TRAIL Trimers using DNA Origami to Promote Clustering of Death Receptor and Cancer Cell Apoptosis.
Sign Up to like & getrecommendations! Published in 2023 at "Small"
DOI: 10.1002/smll.202206160
Abstract: Through inducing death receptor (DR) clustering to activate downstream signaling, tumor necrosis factor related apoptosis inducing ligand (TRAIL) trimers trigger apoptosis of tumor cells. However, the poor agonistic activity of current TRAIL-based therapeutics limits their… read more here.
Keywords: trail; death receptor; dna; trail trimers ... See more keywords
DNA Origami Calibrators for Counting Fluorophores on Single Particles by Flow Cytometry
Sign Up to like & getrecommendations! Published in 2022 at "Small Methods"
DOI: 10.1002/smtd.202101364
Abstract: Flow cytometry (FCM) is a high‐throughput fluorescence‐based technique for multiparameter analysis of individual particles, including cells and nanoparticles. Currently, however, FCM does in many cases not permit proper counting of fluorophore‐tagged markers on individual particles,… read more here.
Keywords: dna; fcm; flow cytometry; microscopy ... See more keywords
Confined Growth of Metal Nanoparticles Within 3D DNA Origami Molds.
Sign Up to like & getrecommendations! Published in 2017 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-6454-3_16
Abstract: Manufacturing prescribed shaped metal nanoparticles promises emerging applications in plasmonics, energy, and disease diagnosis. The key to the shape-controllable synthesis is generating local environments encoded with prescribed geometrical information. Here, we describe a general strategy… read more here.
Keywords: metal; dna origami; growth metal; metal nanoparticles ... See more keywords
A Practical Guide to Molecular Dynamics Simulations of DNA Origami Systems.
Sign Up to like & getrecommendations! Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-8582-1_15
Abstract: The DNA origami method exploits the self-assembly property of nucleic acids to build diverse nanoscale systems. The all-atom molecular dynamics (MD) method has emerged as a powerful computational tool for atomic-resolution characterization of the in… read more here.
Keywords: guide molecular; molecular dynamics; origami systems; dna origami ... See more keywords