Abstract P5-06-06: The Mechanistic Role of BRCA1 DNA and RAD51 Binding in DNA Double-Strand Break Repair
Sign Up to like & getrecommendations! Published in 2025 at "Clinical Cancer Research"
DOI: 10.1158/1557-3265.sabcs24-p5-06-06
Abstract: Genomic instability is a hallmark of cancer, enabling the generation of mutations and gross chromosomal rearrangements to drive neoplastic cell transformation and oncogenesis. The BRCA1-BARD1 protein complex acts to eliminate highly toxic DNA double-strand breaks,… read more here.
Keywords: dna rad51; rad51 binding; brca1; brca1 bard1 ... See more keywords